Abstract The International Molecular Exchange (IMEx) consortium is an international
collaboration between major public interaction data providers to share literature-curation …

Drug development involves a deep understanding of the mechanisms of action and possible
side effects of each drug, and sometimes results in the identification of new and unexpected …

Abstract The UCSC Genome Browser (https://genome. ucsc. edu) provides a web interface
for exploring annotated genome assemblies. The assemblies and annotation tracks are …

IntAct (freely available at http://www. ebi. ac. uk/intact) is an open-source, open data
molecular interaction database populated by data either curated from the literature or from …

Complete knowledge of all direct and indirect interactions between proteins in a given cell
would represent an important milestone towards a comprehensive description of cellular …

An essential prerequisite for any systems-level understanding of cellular functions is to
correctly uncover and annotate all functional interactions among proteins in the cell. Toward …

Abstract The Molecular INTeraction Database (MINT, http://mint. bio. uniroma2. it/mint/) is a
public repository for protein–protein interactions (PPI) reported in peer-reviewed journals …

Network-centered approaches are increasingly used to understand the fundamentals of
biology. However, the molecular details contained in the interaction networks, often …

Identification and analysis of host–pathogen interactions (HPI) is essential to study infectious
diseases. However, HPI data are sparse in existing molecular interaction databases …

Efforts to map the Escherichia coli interactome have identified several hundred
macromolecular complexes, but direct binary protein-protein interactions (PPIs) have not …