[HTML][HTML] Adipose tissue and metabolic health
SM An, SH Cho, JC Yoon - Diabetes & Metabolism Journal, 2023 - synapse.koreamed.org
In this review, we provide a brief synopsis of the connections between adipose tissue and
metabolic health and highlight some recent developments in understanding and exploiting …
metabolic health and highlight some recent developments in understanding and exploiting …
Latest advancements on combating obesity by targeting human brown/beige adipose tissues
R Pan, Y Chen - Frontiers in endocrinology, 2022 - frontiersin.org
Obesity is defined as overaccumulation of white adipose tissue in the body, mainly under the
skin (subcutaneous adiposity) or in the abdominal cavity (visceral adiposity). It could be the …
skin (subcutaneous adiposity) or in the abdominal cavity (visceral adiposity). It could be the …
[HTML][HTML] Architecture of the outbred brown fat proteome defines regulators of metabolic physiology
Brown adipose tissue (BAT) regulates metabolic physiology. However, nearly all
mechanistic studies of BAT protein function occur in a single inbred mouse strain, which has …
mechanistic studies of BAT protein function occur in a single inbred mouse strain, which has …
Mitochondrial matrix protein LETMD1 maintains thermogenic capacity of brown adipose tissue in male mice
Brown adipose tissue (BAT) has abundant mitochondria with the unique capability of
generating heat via uncoupled respiration. Mitochondrial uncoupling protein 1 (UCP1) is …
generating heat via uncoupled respiration. Mitochondrial uncoupling protein 1 (UCP1) is …
[18F]F-AraG imaging reveals association between neuroinflammation and brown- and bone marrow adipose tissue
Brown and brown-like adipose tissues have attracted significant attention for their role in
metabolism and therapeutic potential in diabetes and obesity. Despite compelling evidence …
metabolism and therapeutic potential in diabetes and obesity. Despite compelling evidence …
[HTML][HTML] Gochujang elicits anti-obesity effects by increasing capsaicin-independent brown adipogenesis and thermogenesis in high-fat diet induced obese mice
It is unknown whether Gochujang, a traditional Korean fermented food triggers thermogenic
energy expenditure. This study aims to investigate the impact of Gochujang on brown …
energy expenditure. This study aims to investigate the impact of Gochujang on brown …
Neural circuits of long-term thermoregulatory adaptations to cold temperatures and metabolic demands
The mammalian brain controls heat generation and heat loss mechanisms that regulate
body temperature and energy metabolism. Thermoeffectors include brown adipose tissue …
body temperature and energy metabolism. Thermoeffectors include brown adipose tissue …
[HTML][HTML] Protective effects of puerarin on metabolic diseases: Emphasis on the therapeutical effects and the underlying molecular mechanisms
Q Wan, S Luo, Q Lu, C Guan, H Zhang… - Biomedicine & …, 2024 - Elsevier
Metabolic diseases (MetD) such as diabetes mellitus, obesity, and hyperlipidemia have
become global health challenges. As a naturally occurring plant component, puerarin has …
become global health challenges. As a naturally occurring plant component, puerarin has …
LETMD1 regulates mitochondrial protein synthesis and import to guard brown fat mitochondrial integrity and function
Thermogenic brown adipocytes (BAs) catabolize lipids to generate heat, representing
powerful agents against the growing global obesity epidemic. We and others reported …
powerful agents against the growing global obesity epidemic. We and others reported …
LETMD1, a target of KLF4, hinders endothelial inflammation and pyroptosis: A protective mechanism in the pathogenesis of atherosclerosis
Z Xing, M Du, Y Zhen, J Chen, D Li, R Liu, J Zheng - Cellular Signalling, 2023 - Elsevier
Atherosclerosis (AS), a metabolic disorder, is usually caused by chronic inflammation.
LETM1 Domain-Containing Protein 1 (LETMD1) is a mitochondrial outer membrane protein …
LETM1 Domain-Containing Protein 1 (LETMD1) is a mitochondrial outer membrane protein …