Immune-related adverse events of checkpoint inhibitors

M Ramos-Casals, JR Brahmer, MK Callahan… - Nature reviews Disease …, 2020 - nature.com
Cancer immunotherapies have changed the landscape of cancer treatment during the past
few decades. Among them, immune checkpoint inhibitors, which target PD-1, PD-L1 and …

A review of cancer immunotherapy toxicity

LB Kennedy, AKS Salama - CA: a cancer journal for clinicians, 2020 - Wiley Online Library
Cancer immunotherapies, including checkpoint inhibitors and adoptive cell therapy,
manipulate the immune system to recognize and attack cancer cells. These therapies have …

[HTML][HTML] Society for Immunotherapy of Cancer (SITC) clinical practice guideline on immune checkpoint inhibitor-related adverse events

JR Brahmer, H Abu-Sbeih, PA Ascierto… - … for immunotherapy of …, 2021 - ncbi.nlm.nih.gov
Immune checkpoint inhibitors (ICIs) are the standard of care for the treatment of several
cancers. While these immunotherapies have improved patient outcomes in many clinical …

Small cell lung cancer, version 2.2022, NCCN clinical practice guidelines in oncology

AKP Ganti, BW Loo, M Bassetti, C Blakely… - Journal of the National …, 2021 - jnccn.org
The NCCN Clinical Practice Guidelines in Oncology (NCCN Guidelines) for Small Cell Lung
Cancer (SCLC) provide recommended management for patients with SCLC, including …

[HTML][HTML] Adverse effects of immune-checkpoint inhibitors: epidemiology, management and surveillance

F Martins, L Sofiya, GP Sykiotis, F Lamine… - Nature reviews Clinical …, 2019 - nature.com
Abstract Immune-checkpoint inhibitors (ICIs), including anti-cytotoxic T lymphocyte antigen 4
(CTLA-4), anti-programmed cell death 1 (PD-1) and anti-programmed cell death 1 ligand 1 …

[HTML][HTML] Sintilimab plus platinum and gemcitabine as first-line treatment for advanced or metastatic squamous NSCLC: results from a randomized, double-blind, phase …

C Zhou, L Wu, Y Fan, Z Wang, L Liu, G Chen… - Journal of Thoracic …, 2021 - Elsevier
Introduction The standard chemotherapy for squamous NSCLC (sqNSCLC) includes
platinum plus gemcitabine. Sintilimab, an anti–programmed cell death protein 1 antibody …

Management of immune-related adverse events in patients treated with immune checkpoint inhibitor therapy: American Society of Clinical Oncology Clinical Practice …

JR Brahmer, C Lacchetti, BJ Schneider… - Journal of clinical …, 2018 - ascopubs.org
Purpose To increase awareness, outline strategies, and offer guidance on the
recommended management of immune-related adverse events in patients treated with …

Management of immunotherapy-related toxicities, version 1.2019, NCCN clinical practice guidelines in oncology

JA Thompson, BJ Schneider, J Brahmer… - Journal of the National …, 2019 - jnccn.org
The aim of the NCCN Guidelines for Management of Immunotherapy-Related Toxicities is to
provide guidance on the management of immune-related adverse events resulting from …

[HTML][HTML] Signaling pathways and targeted therapies in lung squamous cell carcinoma: mechanisms and clinical trials

Z Niu, R Jin, Y Zhang, H Li - Signal Transduction and Targeted Therapy, 2022 - nature.com
Lung cancer is the leading cause of cancer-related death across the world. Unlike lung
adenocarcinoma, patients with lung squamous cell carcinoma (LSCC) have not benefitted …

[HTML][HTML] Multidisciplinary clinical guidance on trastuzumab deruxtecan (T-DXd)–related interstitial lung disease/pneumonitis—focus on proactive monitoring, diagnosis …

SM Swain, M Nishino, LH Lancaster, BT Li… - Cancer treatment …, 2022 - Elsevier
Abstract Trastuzumab deruxtecan (T-DXd; DS-8201) is an antibody-drug conjugate targeting
human epidermal growth factor receptor 2. Interstitial lung disease (ILD)/pneumonitis is an …