[HTML][HTML] Macrophage polarization in physiological and pathological pregnancy

Y Yao, XH Xu, L Jin - Frontiers in immunology, 2019 - frontiersin.org
The immunology of pregnancy is complex and poorly defined. During the complex process
of pregnancy, macrophages secrete many cytokines/chemokines and play pivotal roles in …

[HTML][HTML] The immunobiology of preterm labor and birth: intra-amniotic inflammation or breakdown of maternal–fetal homeostasis

N Gomez-Lopez, J Galaz, D Miller… - …, 2022 - rep.bioscientifica.com
In brief The syndrome of preterm labor comprises multiple established and novel etiologies.
This review summarizes the distinct immune mechanisms implicated in preterm labor and …

[HTML][HTML] Single cell transcriptional signatures of the human placenta in term and preterm parturition

R Pique-Regi, R Romero, AL Tarca, ED Sendler, Y Xu… - Elife, 2019 - elifesciences.org
More than 135 million births occur each year; yet, the molecular underpinnings of human
parturition in gestational tissues, and in particular the placenta, are still poorly understood …

[HTML][HTML] Uterine NK cells and macrophages in pregnancy

MM Faas, P De Vos - Placenta, 2017 - Elsevier
The presence of immune cells in the placental bed is important for both mother and child.
Although various immune cells can be found in the placental bed, such as regulatory T cells …

The role of tumor-associated macrophage in breast cancer biology

J Choi, J Gyamfi, H Jang, JS Koo - 2018 - digitum.um.es
Breast cancer is the most commonly diagnosed malignant tumor in women worldwide and
contributes significantly as the primary cause of female cancer related mortality. Hence …

[HTML][HTML] VEGF may contribute to macrophage recruitment and M2 polarization in the decidua

KC Wheeler, MK Jena, BS Pradhan, N Nayak, S Das… - PloS one, 2018 - journals.plos.org
It is increasingly evident that cytokines and growth factors produced in the decidua play a
pivotal role in the regulation of the local immune microenvironment and the establishment of …

CXCL1–CXCR2 axis mediates angiotensin II-induced cardiac hypertrophy and remodelling through regulation of monocyte infiltration

L Wang, YL Zhang, QY Lin, Y Liu, XM Guan… - European heart …, 2018 - academic.oup.com
Aims Chemokine-mediated monocyte infiltration into the damaged heart represents an initial
step in inflammation during cardiac remodelling. Our recent study demonstrates a central …

[HTML][HTML] Single-cell profiling of the human decidual immune microenvironment in patients with recurrent pregnancy loss

C Guo, P Cai, L Jin, Q Sha, Q Yu, W Zhang, C Jiang… - Cell discovery, 2021 - nature.com
Maintaining homeostasis of the decidual immune microenvironment at the maternal–fetal
interface is essential for placentation and reproductive success. Although distinct decidual …

Diverse macrophages polarization in tumor microenvironment

I Rhee - Archives of pharmacal research, 2016 - Springer
Macrophages are traditional innate immune cells that play critical roles in the clearance of
pathogens and the maintenance of tissue homeostasis. Accumulating evidence proves that …

[HTML][HTML] Maternal-fetal immune responses in pregnant women infected with SARS-CoV-2

V Garcia-Flores, R Romero, Y Xu, KR Theis… - Nature …, 2022 - nature.com
Pregnant women represent a high-risk population for severe/critical COVID-19 and mortality.
However, the maternal-fetal immune responses initiated by SARS-CoV-2 infection, and …