The skin is a complex organ that has devised numerous strategies, such as physical,
chemical, and microbiological barriers, to protect the host from external insults. In addition …

With the development of society and the improvement of life quality, more than 500 million
people are affected by diabetes. More than 10% of people with diabetes will suffer from …

Human viruses (those that infect human cells) have been associated with many cancers,
largely due to their mutagenic and functionally manipulative abilities. Despite this, cancer …

Chronic wounds, defined by their resistance to care after four weeks, are a major concern,
affecting millions of patients every year. They can be divided into three types of lesions …

Recent focus on the neonatal intestinal microbiome has advanced our knowledge of the
complex interplay between the intestinal barrier, the developing immune system, and …

The discovery of bacteria in the female urinary bladder has fundamentally changed current
dogma regarding the urinary tract and related urinary disorders. Previous research …

Many relatively common chronic inflammatory skin diseases manifest on the face
(seborrheic dermatitis, rosacea, acne, perioral/periorificial dermatitis, periocular dermatitis …

Abstract Changes in the sequence of an organism's genome, ie, mutations, are the raw
material of evolution. The frequency and location of mutations can be constrained by specific …

Barrier sites such as the skin play a critical role in immune defense. They must maintain
homeostasis with commensals and rapidly detect and limit pathogen invasion. This is …

Diverse bacterial and fungal communities inhabit human-occupied buildings and circulate in
indoor air; however, viral diversity in these man-made environments remains largely …