Cancer researchers have traditionally used the mouse and the rat as staple model
organisms. These animals are very short-lived, reproduce rapidly and are highly prone to …

The naked mole‐rat (Heterocephalus glaber) has fascinated zoologists for at least half a
century. It has also generated considerable biomedical interest not only because of its …

The naked mole rat (Heterocephalus glaber) displays exceptional longevity, with a
maximum lifespan exceeding 30 years,,. This is the longest reported lifespan for a rodent …

The naked mole rat (Heterocephalus glaber) is a strictly subterranean, extraordinarily long-
lived eusocial mammal. Although it is the size of a mouse, its maximum lifespan exceeds 30 …

The ageing of populations worldwide is leading to an unprecedented increase in cancer
cases and fatalities. Understanding the links between cancer and ageing is therefore more …

Aging is characterized by an increasing morbidity and functional decline that eventually
results in the death of an organism. Aging is the largest risk factor for numerous human …

An updated version of the mitochondrial free radical theory of aging (MFRTA) and longevity
is reviewed. Key aspects of the theory are emphasized. Another main focus concerns …

The preternaturally long-lived naked mole-rat, like other long-lived species and
experimental models of extended longevity, is resistant to both endogenous (eg, reactive …

Mammals have evolved a remarkable diversity of ageing rates. Within the single order of
Rodentia, maximum lifespans range from 4 years in mice to 32 years in naked mole rats …

It has been suggested that highly social mammals, such as naked mole rats and humans,
are long-lived due to neoteny (the prolongation of youth). In both species, aging cannot …