Ex Vivo Culture of CTCs: An Emerging Resource to Guide Cancer Therapy
S Maheswaran, DA Haber - Cancer research, 2015 - AACR
With increasing application of targeted therapies and the development of acquired
resistance, much attention is being focused on developing in vitro and in vivo patient …
resistance, much attention is being focused on developing in vitro and in vivo patient …
Recent advances in microfluidic methods in cancer liquid biopsy
Early cancer detection, its monitoring, and therapeutical prediction are highly valuable,
though extremely challenging targets in oncology. Significant progress has been made …
though extremely challenging targets in oncology. Significant progress has been made …
Monolithic chip for high-throughput blood cell depletion to sort rare circulating tumor cells
Circulating tumor cells (CTCs) are a treasure trove of information regarding the location, type
and stage of cancer and are being pursued as both a diagnostic target and a means of …
and stage of cancer and are being pursued as both a diagnostic target and a means of …
All-in-one centrifugal microfluidic device for size-selective circulating tumor cell isolation with high purity
Circulating tumor cells (CTCs) have gained increasing attention owing to their roles in
cancer recurrence and progression. Due to the rarity of CTCs in the bloodstream, an …
cancer recurrence and progression. Due to the rarity of CTCs in the bloodstream, an …
Microfluidic immunomagnetic cell separation from whole blood
SBN Gourikutty, CP Chang, PD Puiu - Journal of Chromatography B, 2016 - Elsevier
Immunomagnetic-based separation has become a viable technique for the separation of
cells and biomolecules. Here we report on the design and analysis of a simple and efficient …
cells and biomolecules. Here we report on the design and analysis of a simple and efficient …
A review on the use of microslit for various applications and its fabrication
T Majumder, PK Patowari - Journal of the Brazilian Society of Mechanical …, 2024 - Springer
Technological advancement, the high cost of energy, and the continuous growing demands
of multitasking devices are the driving forces behind the huge market of compact …
of multitasking devices are the driving forces behind the huge market of compact …
Microfluidic platform for negative enrichment of circulating tumor cells
BNG Sajay, CP Chang, H Ahmad, P Khuntontong… - Biomedical …, 2014 - Springer
Negative enrichment is the preferred approach for tumor cell isolation as it does not rely on
biomarker expression. However, size-based negative enrichment methods suffer from well …
biomarker expression. However, size-based negative enrichment methods suffer from well …
Highlighting the uniqueness in dielectrophoretic enrichment of circulating tumor cells
Circulating tumor cells (CTCs) play an essential role in the metastasis of tumors, and thus
can serve as a valuable prognostic factor for malignant diseases. As a result, the ability to …
can serve as a valuable prognostic factor for malignant diseases. As a result, the ability to …
An integrated on-chip platform for negative enrichment of tumour cells
SBN Gourikutty, CP Chang, DP Poenar - Journal of Chromatography B, 2016 - Elsevier
The study of cancer cells in blood, popularly called circulating tumour cells (CTCs), has
exceptional prospects for cancer risk assessment and analysis. Separation and enrichment …
exceptional prospects for cancer risk assessment and analysis. Separation and enrichment …
Micro+ nanotexturing of substrates to enhance ligand-assisted cancer cell isolation
This paper presents a simple approach to create a two-tiered surface for superior cancer cell
isolation. The idea is inspired by the interactions of cells with a nanotextured basement …
isolation. The idea is inspired by the interactions of cells with a nanotextured basement …