Heterogeneity of triple negative breast cancer: Current advances in subtyping and treatment implications

K Asleh, N Riaz, TO Nielsen - Journal of Experimental & Clinical Cancer …, 2022 - Springer
As the field of translational 'omics has progressed, refined classifiers at both genomic and
proteomic levels have emerged to decipher the heterogeneity of breast cancer in a clinically …

Predictive biomarkers for response to immunotherapy in triple negative breast cancer: promises and challenges

X Wang, L Collet, M Rediti, V Debien… - Journal of clinical …, 2023 - mdpi.com
Triple negative breast cancer (TNBC) is a highly heterogeneous disease with a poor
prognosis and a paucity of therapeutic options. In recent years, immunotherapy has …

Atezolizumab in combination with carboplatin and survival outcomes in patients with metastatic triple-negative breast cancer: the TBCRC 043 phase 2 randomized …

BD Lehmann, VG Abramson, EC Dees, PD Shah… - JAMA …, 2024 - jamanetwork.com
Importance Agents targeting programmed death ligand 1 (PD-L1) have demonstrated
efficacy in triple-negative breast cancer (TNBC) when combined with chemotherapy and are …

Exercise as cancer treatment: a clinical oncology framework for exercise oncology research

KS Courneya, CM Booth - Frontiers in oncology, 2022 - frontiersin.org
Exercise has been proposed as a possible cancer treatment; however, there are an infinite
number of clinical oncology settings involving diverse cancer types and treatment protocols …

From immunohistochemistry to new digital ecosystems: a state-of-the-art biomarker review for precision breast cancer medicine

SM Hacking, E Yakirevich, Y Wang - Cancers, 2022 - mdpi.com
Simple Summary In this state-of-the-art breast biomarker review, we have tried to imagine
and illustrate future, emerging digital breast cancer ecosystems which allow for greater …

Molecular subtype conversion in CTCs as indicator of treatment adequacy associated with metastasis-free survival in breast cancer

ES Grigoryeva, L A. Tashireva, VV Alifanov… - Scientific Reports, 2022 - nature.com
Molecular subtype of breast cancer has a great clinical significance and used as one of the
major criteria for therapeutic strategy. Recently, for anticancer therapy, the trend for …

Designing, analyzing, and interpreting observational studies of physical activity and cancer outcomes from a clinical oncology perspective

KS Courneya, CM Friedenreich - Frontiers in Oncology, 2023 - frontiersin.org
Observational studies may play an important role in evaluating physical activity (PA) as a
cancer treatment; however, few studies have been designed, analyzed, or interpreted from a …

[HTML][HTML] Evolving management of breast cancer in the era of predictive biomarkers and precision medicine

MZ Afzal, LT Vahdat - Journal of Personalized Medicine, 2024 - ncbi.nlm.nih.gov
Breast cancer is the most common cancer among women in the world as well as in the
United States. Molecular and histological differentiation have helped clinicians optimize …

Triple Negative Breast Cancer: Molecular Subtype-Specific Immune Landscapes with Therapeutic Implications

A Syrnioti, S Petousis, LA Newman… - Cancers, 2024 - mdpi.com
Simple Summary Triple Negative Breast Cancer (TNBC) comprises approximately 15–20%
of all breast cancer (BC) cases, is often diagnosed at an advanced stage, and is generally …

Racial and socioeconomic disparities in triple-negative breast cancer treatment

Z Sarfraz, A Sarfraz, O Mehak, R Akhund… - Expert Review of …, 2024 - Taylor & Francis
Introduction Triple-negative breast cancer (TNBC) continues to be a significant concern,
especially among minority populations, where treatment disparities are notably pronounced …