Multiple sclerosis (MS) is an inflammatory demyelinating disease of the central nervous
system (CNS). While the etiology of MS is still largely unknown, scientists believe that the …

Peptidoglycan is a conserved structural component of the bacterial cell wall with molecular
motifs unique to bacteria. The mammalian immune system takes advantage of these …

The microbiota is a crucial modulator of the immune system. Here, we evaluated how its
absence or reduction modifies the inflammatory response in the murine model of …

Multiple sclerosis (MS) is widely acknowledged to be an autoimmune disease affecting the
neuronal myelin structure of the CNS. Autoantigens recognized as the target of this …

Background: The COVID-19 infection is a novel virus that mainly targets the respiratory
system via specific receptors without any coronavirus-targeted therapies. Many efforts have …

The adaptive and innate arms of the immune system are the two pillars of host defense
against environmental pathogens. Multiple sclerosis (MS) is an inflammatory demyelinating …

Background Multiple sclerosis (MS) is a chronic debilitating disease known as one of the
most common neurological dysfunctions in young adults. Recent studies suggest that …

OBJECTIVES: Epstein-Barr virus has been recently associated with the onset of multiple
sclerosis, yet understanding how it elicits autoimmunity remains elusive. We investigated the …

Background Oral infection of mice with P. gingivalis induces periodontal inflammation and
attachment loss. The aim of the present study was to investigate whether infection of mice …

Protein aggregates are a major risk factor for immunogenicity. Until now most studies on
aggregate-driven immunogenicity have focused on linking physicochemical features of the …