Natural products targeting liver X receptors or farnesoid X receptor

J She, T Gu, X Pang, Y Liu, L Tang… - Frontiers in …, 2022 - frontiersin.org
Nuclear receptors (NRs) are a superfamily of transcription factors induced by ligands and
also function as integrators of hormonal and nutritional signals. Among NRs, the liver X …

Traditional herbal medicine discovery for the treatment and prevention of pulmonary arterial hypertension

Z Xue, Y Li, M Zhou, Z Liu, G Fan, X Wang… - Frontiers in …, 2021 - frontiersin.org
Pulmonary arterial hypertension (PAH) is characterized by pulmonary artery remodeling that
may subsequently culminate in right heart failure and premature death. Although there are …

Gut Microbial Metabolite Trimethylamine N-Oxide Aggravates Pulmonary Hypertension

Y Huang, F Lin, R Tang, C Bao, Q Zhou… - American Journal of …, 2022 - atsjournals.org
Trimethylamine N-oxide (TMAO), a metabolite derived from intestine microbial flora,
enhances vascular inflammation in a variety of cardiovascular diseases, and the bacterial …

Biomineralized tetramethylpyrazine-loaded PCL/gelatin nanofibrous membrane promotes vascularization and bone regeneration of rat cranium defects

X Wu, S Ni, T Dai, J Li, F Shao, C Liu, J Wang… - Journal of …, 2023 - Springer
Conventional electrospinning produces nanofibers with smooth surfaces that limit
biomineralization ability. To overcome this disadvantage, we fabricated a …

[HTML][HTML] Mechanistic and therapeutic perspectives of baicalin and baicalein on pulmonary hypertension: A comprehensive review

L Cui, T Yuan, Z Zeng, D Liu, C Liu, J Guo… - Biomedicine & …, 2022 - Elsevier
Pulmonary hypertension (PH) is a chronic and fatal disease, for which new therapeutic
drugs and approaches are needed urgently. Baicalein and baicalin, the active compounds …

HMGB1-induced activation of ER stress contributes to pulmonary artery hypertension in vitro and in vivo

Q Zhang, Y Chen, Q Wang, Y Wang, W Feng… - Respiratory …, 2023 - Springer
Background HMGB1 and ER stress have been considered to participate in the progression
of pulmonary artery hypertension (PAH). However, the molecular mechanism underlying …

中国传统食醋营养健康物质组成研究进展.

吴子航, 张祥龙, 刘丹彤, 魏子翔, 孙承国… - China …, 2022 - search.ebscohost.com
中国传统食醋有着悠久的酿造历史, 不仅风味独特, 而且含有丰富的营养健康成分, 具有抗氧化.
降血脂. 降血糖等多种保健功效. 该文对我国传统食醋中的有机酸. 氨基酸. 多酚. 川 …

Si-Wu-Tang ameliorates fibrotic liver injury via modulating intestinal microbiota and bile acid homeostasis

X Xue, J Wu, M Ding, F Gao, F Zhou, B Xu, M Lu, J Li… - Chinese Medicine, 2021 - Springer
Background Fibrotic liver injury is a progressive scarring event, which may permanently
affect liver function and progress into devastating end-stage liver diseases due to the …

Ligustrazine suppresses platelet-derived growth factor-BB-induced pulmonary artery smooth muscle cell proliferation and inflammation by regulating the PI3K/AKT …

H Huang, L Kong, S Luan, C Qi, F Wu - The American Journal of …, 2021 - World Scientific
Pulmonary arterial hypertension (PAH) is a serious pulmonary vascular disease. Excessive
proliferation of pulmonary artery smooth muscle cells (PASMCs) plays an important role in …

[HTML][HTML] Tetramethylpyrazine: A review of the most recent research

T Xu, G Chen, X Tong, Y Wu, H Xu, X Han… - Pharmacological …, 2022 - Elsevier
Tetramethylpyrazine (TMP) is the main component of functional quality in vinegar. According
to recent studies, TMP has a wide range of pharmacological effects, including a positive …