[HTML][HTML] Ferroptosis: mechanisms and links with diseases

H Yan, T Zou, Q Tuo, S Xu, H Li, AA Belaidi… - Signal transduction and …, 2021 - nature.com
Ferroptosis is an iron-dependent cell death, which is different from apoptosis, necrosis,
autophagy, and other forms of cell death. The process of ferroptotic cell death is defined by …

Mechanism of epithelial‐mesenchymal transition in cancer and its regulation by natural compounds

HL Ang, CD Mohan, MK Shanmugam… - Medicinal research …, 2023 - Wiley Online Library
Epithelial‐mesenchymal transition (EMT) is a complex process with a primordial role in
cellular transformation whereby an epithelial cell transforms and acquires a mesenchymal …

[HTML][HTML] Ferroptosis, necroptosis, and pyroptosis in anticancer immunity

R Tang, J Xu, B Zhang, J Liu, C Liang, J Hua… - Journal of hematology & …, 2020 - Springer
In recent years, cancer immunotherapy based on immune checkpoint inhibitors (ICIs) has
achieved considerable success in the clinic. However, ICIs are significantly limited by the …

[HTML][HTML] Overcoming cancer therapeutic bottleneck by drug repurposing

Z Zhang, L Zhou, N Xie, EC Nice, T Zhang… - Signal transduction and …, 2020 - nature.com
Ever present hurdles for the discovery of new drugs for cancer therapy have necessitated
the development of the alternative strategy of drug repurposing, the development of old …

Recent progress in ferroptosis inducers for cancer therapy

C Liang, X Zhang, M Yang, X Dong - Advanced materials, 2019 - Wiley Online Library
Ferroptosis is a newly discovered form of regulated cell death that is the nexus between
metabolism, redox biology, and human health. Emerging evidence shows the potential of …

Mechanism and medical implications of mammalian autophagy

I Dikic, Z Elazar - Nature reviews Molecular cell biology, 2018 - nature.com
Autophagy is a highly conserved catabolic process induced under various conditions of
cellular stress, which prevents cell damage and promotes survival in the event of energy or …

[HTML][HTML] Naturally occurring anti-cancer compounds: shining from Chinese herbal medicine

H Luo, CT Vong, H Chen, Y Gao, P Lyu, L Qiu, M Zhao… - Chinese medicine, 2019 - Springer
Numerous natural products originated from Chinese herbal medicine exhibit anti-cancer
activities, including anti-proliferative, pro-apoptotic, anti-metastatic, anti-angiogenic effects …

[HTML][HTML] Phytochemistry and pharmacological activity of the genus artemisia

D Bisht, D Kumar, D Kumar, K Dua… - Archives of Pharmacal …, 2021 - Springer
Artemisia and its allied species have been employed for conventional medicine in the
Northern temperate regions of North America, Europe, and Asia for the treatments of …

[HTML][HTML] Plant-derived anticancer agents: A green anticancer approach

J Iqbal, BA Abbasi, T Mahmood, S Kanwal, B Ali… - Asian Pacific Journal of …, 2017 - Elsevier
Cancer is a frightful disease and represents one of the biggest health-care issues for the
human race and demands a proactive strategy for cure. Plants are reservoirs for novel …

DHA inhibits proliferation and induces ferroptosis of leukemia cells through autophagy dependent degradation of ferritin

J Du, T Wang, Y Li, Y Zhou, X Wang, X Yu… - Free Radical Biology …, 2019 - Elsevier
Dihydroartemisinin (DHA) has been shown to be capable of inhibiting cancer growth,
whereas it remains largely elusive that the underlying molecular mechanism of DHA …