In the past two decades, major breakthroughs that improve our understanding of the
pathophysiology and therapy of kidney stones (KS) have been lacking. The disease …

Kidney stone disease (KSD)(alternatively nephrolithiasis or urolithiasis) is a global health
care problem that affects people in almost all of developed and developing countries. Its …

Idiopathic calcium oxalate (CaOx) stones often develop attached to Randall's plaque
present on kidney papillary surfaces. Similar to the plaques formed during vascular …

Kidney stone disease is one of the oldest diseases known to medicine; however, the
mechanisms of stone formation and development remain largely unclear. Over the past …

Kidney stone disease is a crystal concretion formed usually within the kidneys. It is an
increasing urological disorder of human health, affecting about 12% of the world population …

Nanoparticle size plays a central role in determining material properties and performance in
biomedical applications. A wide variety of functional nanomaterials and nano-bioconjugates …

Kidney stone disease causes significant morbidity and increases health care utilization. In
this work, we decipher the cellular and molecular niche of the human renal papilla in …

The pineal gland is a unique organ that synthesizes melatonin as the signaling molecule of
natural photoperiodic environment and as a potent neuronal protective antioxidant. An intact …

Chronic kidney disease (CKD) is a global public health concern and a key determinant of
poor health outcomes. While the burden of CKD is reasonably well defined in developed …

Chronic kidney disease (CKD) is an important public health concern in developed countries
because of both the number of people affected and the high cost of care when prevention …