An update on the effects of vitamin D on the immune system and autoimmune diseases
Vitamin D intervenes in calcium and phosphate metabolism and bone homeostasis.
Experimental studies have shown that 1, 25-dihydroxyvitamin D (calcitriol) generates …
Experimental studies have shown that 1, 25-dihydroxyvitamin D (calcitriol) generates …
Skin senescence: mechanisms and impact on whole-body aging
AC Franco, C Aveleira, C Cavadas - Trends in molecular medicine, 2022 - cell.com
The skin is the largest organ and has a key protective role. Similar to any other tissue, the
skin is influenced not only by intrinsic/chronological aging, but also by extrinsic aging …
skin is influenced not only by intrinsic/chronological aging, but also by extrinsic aging …
Photo-neuro-immuno-endocrinology: How the ultraviolet radiation regulates the body, brain, and immune system
Ultraviolet radiation (UVR) is primarily recognized for its detrimental effects such as
cancerogenesis, skin aging, eye damage, and autoimmune disorders. With exception of …
cancerogenesis, skin aging, eye damage, and autoimmune disorders. With exception of …
The impact of vitamin D on skin aging
G Bocheva, RM Slominski, AT Slominski - International Journal of …, 2021 - mdpi.com
The active metabolites of vitamin D3 (D3) and lumisterol (L3) exert a variety of antiaging and
photoprotective effects on the skin. These are achieved through immunomodulation and …
photoprotective effects on the skin. These are achieved through immunomodulation and …
Melatonin and its metabolites can serve as agonists on the aryl hydrocarbon receptor and peroxisome proliferator-activated receptor gamma
AT Slominski, TK Kim, RM Slominski, Y Song… - International journal of …, 2023 - mdpi.com
Melatonin is widely present in Nature. It has pleiotropic activities, in part mediated by
interactions with high-affinity G-protein-coupled melatonin type 1 and 2 (MT1 and MT2) …
interactions with high-affinity G-protein-coupled melatonin type 1 and 2 (MT1 and MT2) …
Vitamin D in neurological diseases
Vitamin D may have multiple effects on the nervous system and its deficiency can represent
a possible risk factor for the development of many neurological diseases. Recent studies are …
a possible risk factor for the development of many neurological diseases. Recent studies are …
The brain–skin axis in psoriasis—psychological, psychiatric, hormonal, and dermatological aspects
L Marek-Jozefowicz, R Czajkowski… - International journal of …, 2022 - mdpi.com
Psoriasis is a chronic inflammatory skin disease with systemic manifestation, in which
psychological factors play an important role. The etiology of psoriasis is complex and …
psychological factors play an important role. The etiology of psoriasis is complex and …
Vitamin D and COVID-19: An overview of recent evidence
The novel coronavirus severe acute respiratory syndrome (SARS-CoV-2) has progressed
rapidly from an outbreak to a global pandemic, with new variants rapidly emerging …
rapidly from an outbreak to a global pandemic, with new variants rapidly emerging …
The role of CYP3A in health and disease
LS Klyushova, ML Perepechaeva, AY Grishanova - Biomedicines, 2022 - mdpi.com
CYP3A is an enzyme subfamily in the cytochrome P450 (CYP) superfamily and includes
isoforms CYP3A4, CYP3A5, CYP3A7, and CYP3A43. CYP3A enzymes are indiscriminate …
isoforms CYP3A4, CYP3A5, CYP3A7, and CYP3A43. CYP3A enzymes are indiscriminate …
Vitamin D signaling in psoriasis: pathogenesis and therapy
AA Brożyna, RM Slominski, B Nedoszytko… - International Journal of …, 2022 - mdpi.com
Psoriasis is a systemic, chronic, immune-mediated disease that affects approximately 2–3%
of the world's population. The etiology and pathophysiology of psoriasis are still unknown …
of the world's population. The etiology and pathophysiology of psoriasis are still unknown …