Obesity and colorectal cancer: epidemiology, mechanisms and candidate genes

MJ Gunter, MF Leitzmann - The Journal of nutritional biochemistry, 2006 - Elsevier
There is increasing evidence that dysregulation of energy homeostasis is associated with
colorectal carcinogenesis. Epidemiological data have consistently demonstrated a positive …

Nuclear receptor expression links the circadian clock to metabolism

X Yang, M Downes, TY Ruth, AL Bookout, W He… - Cell, 2006 - cell.com
As sensors for fat-soluble hormones and dietary lipids, oscillations in nuclear receptor (NR)
expression in key metabolic tissues may contribute to circadian entrainment of nutrient and …

Cigarette smoking and adenomatous polyps: a meta-analysis

E Botteri, S Iodice, S Raimondi, P Maisonneuve… - Gastroenterology, 2008 - Elsevier
Background & Aims: Through the past 2 decades, a consistent association between
cigarette smoking and colorectal adenomatous polyps, recognized precursor lesions of …

Sporadic colorectal cancer and individual susceptibility: a review of the association studies investigating the role of DNA repair genetic polymorphisms

A Naccarati, B Pardini, K Hemminki… - … Research/Reviews in …, 2007 - Elsevier
Mutations in one of the DNA repair genes are one of the most common reasons for cancer,
and it may be assumed that the individual genetic background modulating the DNA repair …

[HTML][HTML] Development and validation of novel dietary and lifestyle inflammation scores

DA Byrd, SE Judd, WD Flanders, TJ Hartman… - The Journal of …, 2019 - Elsevier
Background Chronically higher inflammation, which may partly result from diet and lifestyle,
is implicated in risk for multiple chronic diseases. The dietary inflammatory index (DII) and …

Inflammation-related gene polymorphisms and colorectal adenoma

MJ Gunter, F Canzian, S Landi, SJ Chanock… - … Biomarkers & Prevention, 2006 - AACR
Chronic inflammation has been reported to be a risk factor for colorectal neoplasia. The
propensity to mount an inflammatory response is modified by germ line variation in cytokine …

Triglyceride–glucose index (TyG index) is a predictor of incident colorectal cancer: a population-based longitudinal study

T Okamura, Y Hashimoto, M Hamaguchi… - BMC endocrine …, 2020 - Springer
Background Colorectal cancer (CRC), which is related with insulin resistance, is a one of the
most common cancers. Triglyceride-glucose index (TyG index) was made for a marker of …

[HTML][HTML] Relation between common polymorphisms in genes related to inflammatory response and colorectal cancer

G Theodoropoulos, I Papaconstantinou… - World journal of …, 2006 - ncbi.nlm.nih.gov
AIM: To investigate the association between common single nucleotide polymorphisms
(SNPs) in inflammatory response-related genes such as interleukin (IL)-6, IL-8, tumor …

Cancer risks in thiazolidinedione users compared to other anti‐diabetic agents

C Koro, S Barrett, N Qizilbash - … and Drug Safety, 2007 - Wiley Online Library
Purpose We conducted three nested case‐control studies to evaluate the risk of breast,
colon, and prostate cancers developing in patients exposed to thiazolidinediones (TZDs) …

Low-penetrance alleles predisposing to sporadic colorectal cancers: a French case-controlled genetic association study

S Küry, B Buecher, S Robiou-du-Pont, C Scoul… - BMC cancer, 2008 - Springer
Background Sporadic colorectal cancers (CRC) are multifactorial diseases resulting from the
combined effects of numerous genetic, environmental and behavioral risk factors. Genetic …