Since the second half of the twentieth century, intracranial electroencephalography (iEEG),
including both electrocorticography (ECoG) and stereo-electroencephalography (sEEG) …

Designing bioelectronic devices that seamlessly integrate with the human body is a
technological pursuit of great importance. Bioelectronic medical devices that reliably and …

Recent advances in multi-electrode array technology have made it possible to monitor large
neuronal ensembles at cellular resolution in animal models. In humans, however, current …

Neuropixels are silicon-based electrophysiology-recording probes with high channel count
and recording-site density. These probes offer a turnkey platform for measuring neural …

Human pluripotent stem cell (hPSC)-derived neuron cultures have emerged as models of
electrical activity in the human brain. Microelectrode arrays (MEAs) measure changes in the …

Background Electrical neuromodulation via direct electrical stimulation (DES) is an
increasingly common therapy for a wide variety of neuropsychiatric diseases. Unfortunately …

Intracellular access with high spatiotemporal resolution can enhance the understanding of
how neurons or cardiomyocytes regulate and orchestrate network activity and how this …

Cutaneous electrodes are routinely used for noninvasive electrophysiological sensing of
signals from the brain, the heart, and the neuromuscular system. These bioelectronic signals …

Electrophysiological stimulation has been widely adopted for clinical diagnostic and
therapeutic treatments for modulation of neuronal activity. Safety is a primary concern in an …

Purpose Human neuronal activity, recorded in vivo from microelectrodes, may offer valuable
insights into physiological mechanisms underlying human cognition and pathophysiological …