Traumatic brain injuries

K Blennow, DL Brody, PM Kochanek, H Levin… - Nature reviews Disease …, 2016 - nature.com
Traumatic brain injuries (TBIs) are clinically grouped by severity: mild, moderate and severe.
Mild TBI (the least severe form) is synonymous with concussion and is typically caused by …

What is the physiological time to recovery after concussion? A systematic review

J Kamins, E Bigler, T Covassin, L Henry… - British journal of sports …, 2017 - bjsm.bmj.com
Aim or objective The aim of this study is to consolidate studies of physiological measures
following sport-related concussion (SRC) to determine if a time course of postinjury altered …

Acute evaluation of sport-related concussion and implications for the Sport Concussion Assessment Tool (SCAT6) for adults, adolescents and children: a systematic …

RJ Echemendia, JS Burma, JM Bruce… - British journal of sports …, 2023 - bjsm.bmj.com
Objectives To systematically review the scientific literature regarding the acute assessment
of sport-related concussion (SRC) and provide recommendations for improving the Sport …

Fluid biomarkers for mild traumatic brain injury and related conditions

H Zetterberg, K Blennow - Nature reviews neurology, 2016 - nature.com
Diagnostic and prognostic biomarkers for mild traumatic brain injury (TBI), also known as
concussion, remain a major unmet clinical need. Moderate to severe TBI can be diagnosed …

Role of advanced neuroimaging, fluid biomarkers and genetic testing in the assessment of sport-related concussion: a systematic review

M McCrea, T Meier, D Huber, A Ptito… - British journal of sports …, 2017 - bjsm.bmj.com
Objective To conduct a systematic review of published literature on advanced neuroimaging,
fluid biomarkers and genetic testing in the assessment of sport-related concussion (SRC) …

Blood biomarkers for brain injury: What are we measuring?

K Kawata, CY Liu, SF Merkel, SH Ramirez… - Neuroscience & …, 2016 - Elsevier
Accurate diagnosis for mild traumatic brain injury (mTBI) remains challenging, as prognosis
and return-to-play/work decisions are based largely on patient reports. Numerous …

Role of biomarkers and emerging technologies in defining and assessing neurobiological recovery after sport-related concussion: a systematic review

JB Tabor, BL Brett, L Nelson, T Meier… - British journal of sports …, 2023 - bjsm.bmj.com
Objective Determine the role of fluid-based biomarkers, advanced neuroimaging, genetic
testing and emerging technologies in defining and assessing neurobiological recovery after …

Mechanical disruption of the blood–brain barrier following experimental concussion

VE Johnson, MT Weber, R Xiao, DK Cullen… - Acta …, 2018 - Springer
Although concussion is now recognized as a major health issue, its non-lethal nature has
limited characterization of the underlying pathophysiology. In particular, potential …

The potential for animal models to provide insight into mild traumatic brain injury: translational challenges and strategies

SR Shultz, SJ McDonald, CV Haar, A Meconi… - Neuroscience & …, 2017 - Elsevier
Mild traumatic brain injury (mTBI) is a common health problem. There is tremendous
variability and heterogeneity in human mTBI, including mechanisms of injury, biomechanical …

[HTML][HTML] The current state of biomarkers of mild traumatic brain injury

HJ Kim, JW Tsao, AG Stanfill - JCI insight, 2018 - ncbi.nlm.nih.gov
Mild traumatic brain injury (mTBI) is a common occurrence, with over 3 million cases
reported every year in the United States. While research into the underlying pathophysiology …