Role of autophagy in environmental neurotoxicity

C Pellacani, LG Costa - Environmental pollution, 2018 - Elsevier
Human exposure to neurotoxic pollutants (eg metals, pesticides and other chemicals) is
recognized as a key risk factor in the pathogenesis of neurodegenerative disorders …

Reactive oxygen species and mitogen-activated protein kinase induce apoptotic death of SH-SY5Y cells in response to fipronil

YW Ki, JE Lee, JH Park, IC Shin, HC Koh - Toxicology letters, 2012 - Elsevier
There are multiple lines of evidence showing that environmental toxicants including
pesticides may contribute to neuronal cell death. Fipronil (FPN) is a phenylpyrazole …

Akt/GSK3β signaling is involved in fipronil-induced apoptotic cell death of human neuroblastoma SH-SY5Y cells

JE Lee, JS Kang, YW Ki, SH Lee, SJ Lee, KS Lee… - Toxicology letters, 2011 - Elsevier
Fipronil (FPN) is a phenylpyrazole insecticide acted on insect gamma-aminobutyric acid
(GABA) receptors. Although action of FPN is restricted on insect neuronal or muscular …

Chronic toxicity testing including transcriptomics-based molecular profiling in Cloeon dipterum

K Germing, SU Ayobahan, H Reinwald, M Vogt… - Environmental Sciences …, 2023 - Springer
The so-called EPT taxa have been shown to be highly sensitive to various environmental
pollutants. However, there are only few published studies on toxicity testing with EPT …

Potential autophagy enhancers protect against fipronil-induced apoptosis in SH-SY5Y cells

JH Park, JE Lee, SJ Lee, SJ Park, KH Park, M Jeong… - Toxicology letters, 2013 - Elsevier
Oxidative stress created by environmental toxicants activates several signaling pathways.
Autophagy is one of the first lines of defense against oxidative stress damage. The …

Fipronil induces apoptosis and cell cycle arrest in porcine oocytes during in vitro maturation

W Zhou, YJ Niu, ZW Nie, YH Kim, KT Shin, J Guo… - Apoptosis, 2019 - Springer
Fipronil (FPN) is a widely used phenylpyrazole pesticide that can kill pests by blocking γ-
aminobutyric acid (GABA)-gated chloride channels. In addition, there are lack of studies on …

Inhibition of protein kinase C decreases sensitivity of GABA receptor subtype to fipronil insecticide in insect neurosecretory cells

L Murillo, A Hamon, Z Es-Salah-Lamoureux, V Itier… - NeuroToxicology, 2011 - Elsevier
Phosphorylation by serine/threonine kinases has been described as a new mechanism for
regulating the effects of insecticides on insect neuronal receptors and channels. Although …

Fipronil mobility and transformation in undisturbed soil columns

NS Chatterjee, S Gupta - Bulletin of environmental contamination and …, 2010 - Springer
The downward movement of fipronil and its two toxic metabolites ie sulfone and desulfinyl
were studied in undisturbed soil columns. Mobility behavior of two different formulations of …

Veterinary pesticides

KN Woodward - 2012 - books.rsc.org
12.1 Background Veterinary pesticides are used to treat a number of conditions in animals,
usually ectoparasites. In fact 'veterinary pesticides' is a slightly misleading term. In most …

[HTML][HTML] A bird's-eye view on the modern genetics workflow and its potential applicability to the locust problem

M Bakkali - Comptes Rendus. Biologies, 2013 - comptes-rendus.academie-sciences …
Résumé Genetics is an immense science and the current developments in its methods and
techniques as well as the fast emerging tools make it one of the most powerful biological …