Glial responses to implanted electrodes in the brain

JW Salatino, KA Ludwig, TDY Kozai… - Nature biomedical …, 2017 - nature.com
The use of implants that can electrically stimulate or record electrophysiological or
neurochemical activity in nervous tissue is rapidly expanding. Despite remarkable results in …

A materials roadmap to functional neural interface design

SM Wellman, JR Eles, KA Ludwig… - Advanced functional …, 2018 - Wiley Online Library
Advancements in neurotechnologies for electrophysiology, neurochemical sensing,
neuromodulation, and optogenetics are revolutionizing scientific understanding of the brain …

[HTML][HTML] Probing and regulating dysfunctional circuits using deep brain stimulation

AM Lozano, N Lipsman - Neuron, 2013 - cell.com
Despite the best available medical treatments, many patients continue to be disabled by
neurologic and psychiatric disorders, resulting in a large unmet need. Advances in imaging …

[HTML][HTML] Advances in closed-loop deep brain stimulation devices

M Parastarfeizabadi, AZ Kouzani - Journal of neuroengineering and …, 2017 - Springer
Background Millions of patients around the world are affected by neurological and
psychiatric disorders. Deep brain stimulation (DBS) is a device-based therapy that could …

[HTML][HTML] Fast scan cyclic voltammetry: Chemical sensing in the brain and beyond

JG Roberts, LA Sombers - Analytical chemistry, 2018 - ncbi.nlm.nih.gov
In this review we describe the electroanalytical method known as fast-scan cyclic
voltammetry (FSCV), how it has advanced over the years, and in what way (s) it is impacting …

Electrochemical analysis of neurotransmitters

ES Bucher, RM Wightman - Annual review of analytical …, 2015 - annualreviews.org
Chemical signaling through the release of neurotransmitters into the extracellular space is
the primary means of communication between neurons. More than four decades ago, Ralph …

[HTML][HTML] Deep brain stimulation: a review of the open neural engineering challenges

M Vissani, IU Isaias, A Mazzoni - Journal of neural engineering, 2020 - iopscience.iop.org
Objective. Deep brain stimulation (DBS) is an established and valid therapy for a variety of
pathological conditions ranging from motor to cognitive disorders. Still, much of the DBS …

[HTML][HTML] Carbon-based neural electrodes: Promises and challenges

M Devi, M Vomero, E Fuhrer… - Journal of Neural …, 2021 - iopscience.iop.org
Neural electrodes are primary functional elements of neuroelectronic devices designed to
record neural activity based on electrochemical signals. These electrodes may also be …

Neuroadhesive L1 coating attenuates acute microglial attachment to neural electrodes as revealed by live two-photon microscopy

JR Eles, AL Vazquez, NR Snyder, C Lagenaur… - Biomaterials, 2017 - Elsevier
Implantable neural electrode technologies for chronic neural recordings can restore
functional control to paralysis and limb loss victims through brain-machine interfaces. These …

[HTML][HTML] A neurochemical closed-loop controller for deep brain stimulation: toward individualized smart neuromodulation therapies

PJ Grahn, GW Mallory, OU Khurram, BM Berry… - Frontiers in …, 2014 - frontiersin.org
Current strategies for optimizing deep brain stimulation (DBS) therapy involve multiple
postoperative visits. During each visit, stimulation parameters are adjusted until desired …