Objectives Hot melt extrusion (HME) as a technique for producing amorphous solid
dispersion (ASD) has been widely used in pharmaceutical research. The biggest challenge …

Amorphous drug–polymer solid dispersions have the potential to enhance the dissolution
performance and thus bioavailability of BCS class II drug compounds. The principle …

The following review focuses on the manufacturing and parameterizing of ocular drug
delivery systems (DDS) using polymeric materials to create soft contact lenses. It discusses …

To improve solubility of tadalafil (Td), a poorly soluble drug substance (3 μg/ml) belonging to
the II class of the Biopharmaceutical Classification System, its six different solid dispersions …

In this study, the amorphous solid dispersions of cyclosporine A (CsA-ASDs) were prepared
by hot melt extrusion (HME) with PVP K12 as carrier to improve the oral bioavailability of …

The present study aimed to develop an amorphous solid dispersion (SD) of nobiletin (NOB),
a citrus polymethoxylated flavone, with the aim of improving its biopharmaceutical and …

The present study aimed to develop a self-micellizing solid dispersion (SMSD) of
cyclosporine A (CsA) using an amphiphilic block copolymer, poly [MPC-co-BMA], to improve …

A variety of nanoscale delivery systems have been shown to enhance the oral absorption of
poorly water-soluble and poorly permeable drugs. However, the performance of these …

The present study aimed to develop an amorphous solid dispersion (ASD) of cyclosporine A
(CsA) by a fine droplet drying (FDD) process for improvement in oral absorption of CsA. CsA …

In view of the increasing interest in injectable controlled release formulations for the
treatment of chronic diseases, injectable polymeric microspheres consisting of a surface …