Oestradiol as a neuromodulator of learning and memory

LR Taxier, KS Gross, KM Frick - Nature Reviews Neuroscience, 2020 - nature.com
Although hormones such as glucocorticoids have been broadly accepted in recent decades
as general neuromodulators of memory processes, sex steroid hormones such as the potent …

The peri-menopause in a woman's life: a systemic inflammatory phase that enables later neurodegenerative disease

M McCarthy, AP Raval - Journal of neuroinflammation, 2020 - Springer
The peri-menopause or menopausal transition—the time period that surrounds the final
years of a woman's reproductive life—is associated with profound reproductive and …

The neuroprotective actions of oestradiol and oestrogen receptors

MA Arevalo, I Azcoitia, LM Garcia-Segura - Nature Reviews …, 2015 - nature.com
Hormones regulate homeostasis by communicating through the bloodstream to the body's
organs, including the brain. As homeostatic regulators of brain function, some hormones …

Sex differences in the brain: Implications for behavioral and biomedical research

E Choleris, LAM Galea, F Sohrabji, KM Frick - … & Biobehavioral Reviews, 2018 - Elsevier
Biological differences between males and females are found at multiple levels. However,
females have too often been under-represented in behavioral neuroscience research, which …

Insulin-like growth factor-1 and neuroinflammation

JL Labandeira-Garcia, MA Costa-Besada… - Frontiers in aging …, 2017 - frontiersin.org
Insulin-like growth factor-1 (IGF-1) effects on aging and neurodegeneration is still
controversial. However, it is widely admitted that IGF-1 is involved in the neuroinflammatory …

Sex differences in stroke: review of current knowledge and evidence

RL Girijala, F Sohrabji, RL Bush - Vascular medicine, 2017 - journals.sagepub.com
Stroke is a leading cause of death among women in the United States, and women are more
affected by stroke than men. With women living longer than men, women experience not …

Estrogens as neuroprotectants: estrogenic actions in the context of cognitive aging and brain injury

EB Engler-Chiurazzi, CM Brown, JM Povroznik… - Progress in …, 2017 - Elsevier
There is ample empirical evidence to support the notion that the biological impacts of
estrogen extend beyond the gonads to other bodily systems, including the brain and …

Brain neurotrauma: molecular, neuropsychological, and rehabilitation aspects

FH Kobeissy - 2015 - books.google.com
With the contribution from more than one hundred CNS neurotrauma experts, this book
provides a comprehensive and up-to-date account on the latest developments in the area of …

Why estrogens matter for behavior and brain health

LAM Galea, KM Frick, E Hampson, F Sohrabji… - Neuroscience & …, 2017 - Elsevier
Abstract The National Institutes of Health (NIH) has required the inclusion of women in
clinical studies since 1993, which has enhanced our understanding of how biological sex …

An antagomir to microRNA Let7f promotes neuroprotection in an ischemic stroke model

A Selvamani, P Sathyan, RC Miranda, F Sohrabji - PloS one, 2012 - journals.plos.org
We previously showed that middle-aged female rats sustain a larger infarct following
experimental stroke as compared to younger female rats, and paradoxically, estrogen …