Implantable aptamer–field-effect transistor neuroprobes for in vivo neurotransmitter monitoring

C Zhao, KM Cheung, IW Huang, H Yang… - Science …, 2021 - science.org
While tools for monitoring in vivo electrophysiology have been extensively developed,
neurochemical recording technologies remain limited. Nevertheless, chemical …

Highly selective and sensitive fluorescent biosensor for the detection of serotonin and its metabolite by Eu3+-Doped Metal-Organic framework

YF Zhong, GM Bao, M Qiu, YF Xia, W Li, YQ Tao… - Chemical Engineering …, 2022 - Elsevier
Monoamine neurotransmitters such as L-epinephrine (EPI), norepinephrine (NE), dopamine
(DA), and serotonin (ST) are important biomarkers for neurological diseases. However …

Multiplexed monitoring of neurochemicals via electrografting-enabled site-selective functionalization of aptamers on field-effect transistors

Z Gao, G Wu, Y Song, H Li, Y Zhang… - Analytical …, 2022 - ACS Publications
Neurochemical corelease has received much attention in understanding brain activity and
cognition. Despite many attempts, the multiplexed monitoring of coreleased neurochemicals …

Skin-inspired soft bioelectronic materials, devices and systems

C Zhao, J Park, SE Root, Z Bao - Nature Reviews Bioengineering, 2024 - nature.com
Bioelectronic devices and components made from soft, polymer-based and hybrid electronic
materials form natural interfaces with the human body. Advances in the molecular design of …

Stable in-vivo electrochemical sensing of tonic serotonin levels using PEDOT/CNT-coated glassy carbon flexible microelectrode arrays.

E Castagnola, EM Robbins, DD Krahe, B Wu… - Biosensors and …, 2023 - Elsevier
Chronic sampling of tonic serotonin (5-hydroxytryptamine, 5-HT) concentrations in the brain
is critical for tracking neurological disease development and the time course of …

Maximizing electrochemical information: A perspective on background-inclusive fast voltammetry

CS Movassaghi, M Alcañiz Fillol, KT Kishida… - Analytical …, 2024 - ACS Publications
This perspective encompasses a focused review of the literature leading to a tipping point in
electroanalytical chemistry. We tie together the threads of a “revolution” quietly in the making …

Simultaneous serotonin and dopamine monitoring across timescales by rapid pulse voltammetry with partial least squares regression

CS Movassaghi, KA Perrotta, H Yang, R Iyer… - Analytical and …, 2021 - Springer
Many voltammetry methods have been developed to monitor brain extracellular dopamine
levels. Fewer approaches have been successful in detecting serotonin in vivo. No …

Clinical applications of neurochemical and electrophysiological measurements for closed-loop neurostimulation

JB Price, AE Rusheen, AS Barath, JMR Cabrera… - Neurosurgical …, 2020 - thejns.org
The development of closed-loop deep brain stimulation (DBS) systems represents a
significant opportunity for innovation in the clinical application of neurostimulation therapies …

Cocaine-Induced Changes in Tonic Dopamine Concentrations Measured Using Multiple-Cyclic Square Wave Voltammetry in vivo

J Yuen, A Goyal, AE Rusheen, AZ Kouzani… - Frontiers in …, 2021 - frontiersin.org
For over 40 years, in vivo microdialysis techniques have been at the forefront in measuring
the effects of illicit substances on brain tonic extracellular levels of dopamine that underlie …

Tonic Serotonin Measurements In Vivo Using N-Shaped Multiple Cyclic Square Wave Voltammetry

H Shin, A Goyal, JH Barnett, AE Rusheen… - Analytical …, 2021 - ACS Publications
Here, we present the development of a novel voltammetric technique, N-shaped multiple
cyclic square wave voltammetry (N-MCSWV) and its application in vivo. It allows quantitative …