Life in the human stomach: persistence strategies of the bacterial pathogen Helicobacter pylori

NR Salama, ML Hartung, A Müller - Nature Reviews Microbiology, 2013 - nature.com
The bacterial pathogen Helicobacter pylori has co-evolved with humans and colonizes
approximately 50% of the human population, but only causes overt gastric disease in a …

Helicobacter pylori and Gastric Cancer: Factors That Modulate Disease Risk

LE Wroblewski, RM Peek Jr… - Clinical microbiology …, 2010 - Am Soc Microbiol
Helicobacter pylori is a gastric pathogen that colonizes approximately 50% of the world's
population. Infection with H. pylori causes chronic inflammation and significantly increases …

Epidemiology, diagnosis, and management of esophageal adenocarcinoma

JH Rubenstein, NJ Shaheen - Gastroenterology, 2015 - Elsevier
Esophageal adenocarcinoma (EAC) is rapidly increasing in incidence in Western cultures.
Barrett's esophagus is the presumed precursor lesion for this cancer. Several other risk …

Pathogenesis of Helicobacter pylori Infection

JG Kusters, AHM Van Vliet… - Clinical microbiology …, 2006 - Am Soc Microbiol
Helicobacter pylori is the first formally recognized bacterial carcinogen and is one of the
most successful human pathogens, as over half of the world's population is colonized with …

Helicobacter pylori immune escape is mediated by dendritic cell–induced Treg skewing and Th17 suppression in mice

JY Kao, M Zhang, MJ Miller, JC Mills, B Wang, M Liu… - Gastroenterology, 2010 - Elsevier
BACKGROUND & AIMS: Helicobacter pylori infection increases gastric regulatory T cell
(Treg) response, which may contribute to H pylori immune escape. We hypothesize that H …

Role of Innate Immunity in Helicobacter pylori-Induced Gastric Malignancy

RM Peek Jr, C Fiske, KT Wilson - Physiological reviews, 2010 - journals.physiology.org
Helicobacter pylori colonizes the majority of persons worldwide, and the ensuing gastric
inflammatory response is the strongest singular risk factor for peptic ulceration and gastric …

DC-derived IL-18 drives Treg differentiation, murine Helicobacter pylori–specific immune tolerance, and asthma protection

M Oertli, M Sundquist, I Hitzler… - The Journal of …, 2012 - Am Soc Clin Investig
Persistent colonization with the gastric bacterial pathogen Helicobacter pylori causes
gastritis and predisposes infected individuals to gastric cancer. Conversely, it is also linked …

[HTML][HTML] Exploring alternative treatments for Helicobacter pylori infection

G Ayala, WI Escobedo-Hinojosa… - World journal of …, 2014 - ncbi.nlm.nih.gov
Helicobacter pylori (H. pylori) is a successful pathogen that can persist in the stomach of an
infected person for their entire life. It provokes chronic gastric inflammation that leads to the …

Helicobacter pylori Persistence: an Overview of Interactions between H. pylori and Host Immune Defenses

HMS Algood, TL Cover - Clinical microbiology reviews, 2006 - Am Soc Microbiol
Helicobacter pylori is a gram-negative bacterium that persistently colonizes more than half of
the global human population. In order to successfully colonize the human stomach, H. pylori …

Immunology of Helicobacter pylori: insights into the failure of the immune response and perspectives on vaccine studies

KT Wilson, JE Crabtree - Gastroenterology, 2007 - Elsevier
Helicobacter pylori infects the stomach of half of the human population worldwide and
causes chronic active gastritis, which can lead to peptic ulcer disease, gastric …