[HTML][HTML] Development of a robust and convenient dual-reporter high-throughput screening assay for SARS-CoV-2 antiviral drug discovery

W Chiu, J Schepers, T Francken, L Vangeel, K Abbasi… - Antiviral research, 2023 - Elsevier
Massive efforts on both vaccine development and antiviral research were launched to
combat the new severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). We …

Illuminating bunyavirus entry into host cells with fluorescence

Y Gu, PY Lozach - Molecular Microbiology, 2024 - Wiley Online Library
Bunyavirales constitute the largest order of enveloped RNA viruses, many members of
which cause severe diseases in humans and domestic animals. In recent decades …

Multiplexed multicolor antiviral assay amenable for high-throughput research

LH Li, W Chiu, YA Huang, M Rasulova… - Nature …, 2024 - nature.com
To curb viral epidemics and pandemics, antiviral drugs are needed with activity against
entire genera or families of viruses. Here, we develop a cell-based multiplex antiviral assay …

A Robust Phenotypic High-Throughput Antiviral Assay for the Discovery of Rabies Virus Inhibitors

X Wang, W Chiu, H Klaassen, A Marchand, P Chaltin… - Viruses, 2023 - mdpi.com
Rabies virus (RABV) causes severe neurological symptoms in mammals. The disease is
almost inevitably lethal as soon as clinical symptoms appear. The use of rabies …