[HTML][HTML] Design of therapeutic biomaterials to control inflammation

Z Tu, Y Zhong, H Hu, D Shao, R Haag… - Nature Reviews …, 2022 - nature.com
Inflammation plays an important role in the response to danger signals arising from damage
to our body and in restoring homeostasis. Dysregulated inflammatory responses occur in …

[HTML][HTML] Neutrophil extracellular traps in systemic autoimmune and autoinflammatory diseases

G Wigerblad, MJ Kaplan - Nature Reviews Immunology, 2023 - nature.com
Systemic autoimmune diseases are characterized by the failure of the immune system to
differentiate self from non-self. These conditions are associated with significant morbidity …

[HTML][HTML] Vascular occlusion by neutrophil extracellular traps in COVID-19

M Leppkes, J Knopf, E Naschberger, A Lindemann… - …, 2020 - thelancet.com
Background Coronavirus induced disease 2019 (COVID-19) can be complicated by severe
organ damage leading to dysfunction of the lungs and other organs. The processes that …

[HTML][HTML] Devilishly radical NETwork in COVID-19: Oxidative stress, neutrophil extracellular traps (NETs), and T cell suppression

G Schönrich, MJ Raftery, Y Samstag - Advances in biological regulation, 2020 - Elsevier
Abstract Pandemic coronavirus disease 2019 (COVID-19) is caused by severe acute
respiratory syndrome coronavirus 2 (SARS-CoV-2) and poses an unprecedented challenge …

[HTML][HTML] Neutrophil extracellular traps infiltrate the lung airway, interstitial, and vascular compartments in severe COVID-19

C Radermecker, N Detrembleur, J Guiot… - Journal of Experimental …, 2020 - rupress.org
Infection with SARS-CoV-2 is causing a deadly and pandemic disease called coronavirus
disease–19 (COVID-19). While SARS-CoV-2–triggered hyperinflammatory tissue-damaging …

Neutrophil extracellular traps in the pathology of cancer and other inflammatory diseases

M Herre, J Cedervall, N Mackman… - Physiological …, 2023 - journals.physiology.org
Neutrophil extracellular trap (NET) formation, first described in 2004 as a previously
unknown strategy of neutrophils to fight microbes, has attracted an increasing interest in the …

Neutrophil extracellular traps participate in cardiovascular diseases: recent experimental and clinical insights

Y Döring, P Libby, O Soehnlein - Circulation research, 2020 - Am Heart Assoc
Neutrophil extracellular traps (NETs) have recently emerged as a newly recognized
contributor to venous and arterial thrombosis. These strands of DNA extruded by activated or …

The NLRP3 inflammasome and COVID-19: Activation, pathogenesis and therapeutic strategies

N Zhao, B Di, L Xu - Cytokine & growth factor reviews, 2021 - Elsevier
Abstract Coronavirus disease 2019 (COVID-19), caused by severe acute respiratory
syndrome coronavirus 2 (SARS-CoV-2), exhibits a wide spectrum of clinical presentations …

[HTML][HTML] Neutrophil extracellular traps (NETs) take the central stage in driving autoimmune responses

E Fousert, R Toes, J Desai - Cells, 2020 - mdpi.com
Following fifteen years of research, neutrophil extracellular traps (NETs) are widely reported
in a large range of inflammatory infectious and non-infectious diseases. Cumulating …

[HTML][HTML] Neutrophil extracellular traps activate proinflammatory functions of human neutrophils

D Dömer, T Walther, S Möller, M Behnen… - Frontiers in …, 2021 - frontiersin.org
Neutrophil extracellular traps (NETs) consist of decondensed nuclear chromatin that is
associated with proteins and are released by neutrophils during an inflammatory response …