Gene expression and regulation. The two forms of a prolonged activated partial
thromboplastin time (APTT), plasma kininogens, HK and low molecular weight kininogen a …

Coagulation and innate immunity are linked evolutionary processes that orchestrate the host
defence against invading pathogens and injury. The complement system is integral to innate …

Abstract p32/gC1qR/C1QBP/HABP1 is a mitochondrial/cell surface protein overexpressed in
certain cancer cells. Here we show that knocking down p32 expression in human cancer …

The kallikrein-kinin system is an endogenous metabolic cascade, triggering of which results
in the release of vasoactive kinins (bradykinin-related peptides). This complex system …

Remarkable progress in understanding the pathophysiology and underlying mechanisms of
hereditary angioedema has led to the development of effective treatment for this disorder …

Bradykinin is formed by the interaction of factor XII, prekallikrein, and high-molecular-weight
kininogen on negatively charged inorganic surfaces (silicates, urate, and pyrophosphate) or …

InlB is a Listeria monocytogenes protein that promotes entry of the bacterium into
mammalian cells by stimulating tyrosine phosphorylation of the adaptor proteins Gab1, Cbl …

Human p32 (also known as SF2-associated p32, p32/TAP, and gC1qR) is a conserved
eukaryotic protein that localizes predominantly in the mitochondrial matrix. It is thought to be …

The plasma bradykinin-forming cascade and the complement pathways share many
elements, including cross-activation, common control mechanisms, and shared binding …

Our recent investigations have postulated a human umbilical vein endothelial cell (HUVEC)-
associated prekallikrein activator (PKA). When prekallikrein (PK) assembles on high …