History of myeloid-derived suppressor cells

JE Talmadge, DI Gabrilovich - Nature Reviews Cancer, 2013 - nature.com
Tumour-induced granulocytic hyperplasia is associated with tumour vasculogenesis and
escape from immunity via T cell suppression. Initially, these myeloid cells were identified as …

[HTML][HTML] Challenges and strategies for in situ endothelialization and long-term lumen patency of vascular grafts

Y Zhuang, C Zhang, M Cheng, J Huang, Q Liu… - Bioactive Materials, 2021 - Elsevier
Vascular diseases are the most prevalent cause of ischemic necrosis of tissue and organ,
which even result in dysfunction and death. Vascular regeneration or artificial vascular graft …

Integrins in angiogenesis and lymphangiogenesis

CJ Avraamides, B Garmy-Susini, JA Varner - Nature Reviews Cancer, 2008 - nature.com
Blood vessels promote tumour growth, and both blood and lymphatic vessels facilitate
tumour metastasis by serving as conduits for the transport of tumour cells to new sites …

Hypoxia-inducible factor-1-dependent mechanisms of vascularization and vascular remodelling

S Rey, GL Semenza - Cardiovascular research, 2010 - academic.oup.com
The vascular system delivers oxygen and nutrients to every cell in the vertebrate organism.
Hypoxia-inducible factor 1 (HIF-1) is a master regulator of hypoxic/ischaemic vascular …

The SDF-1–CXCR4 signaling pathway: a molecular hub modulating neo-angiogenesis

I Petit, D Jin, S Rafii - Trends in immunology, 2007 - cell.com
Pro-angiogenic bone marrow (BM) cells include subsets of hematopoietic cells that provide
vascular support and endothelial progenitor cells (EPCs), which under certain permissive …

Vascular repair by endothelial progenitor cells

A Zampetaki, JP Kirton, Q Xu - Cardiovascular research, 2008 - academic.oup.com
Accumulating evidence indicates the impact of endothelial progenitor cells (EPCs) in
vascular repair. In patients, the number of EPCs is negatively correlated with the severity of …

Postischemic revascularization: from cellular and molecular mechanisms to clinical applications

JS Silvestre, DM Smadja, BI Levy - Physiological reviews, 2013 - journals.physiology.org
After the onset of ischemia, cardiac or skeletal muscle undergoes a continuum of molecular,
cellular, and extracellular responses that determine the function and the remodeling of the …

Hypoxic preconditioning enhances the benefit of cardiac progenitor cell therapy for treatment of myocardial infarction by inducing CXCR4 expression

YL Tang, W Zhu, M Cheng, L Chen, J Zhang… - Circulation …, 2009 - Am Heart Assoc
Myocardial infarction rapidly depletes the endogenous cardiac progenitor cell pool, and the
inefficient recruitment of exogenously administered progenitor cells limits the effectiveness …

Number and function of endothelial progenitor cells as a marker of severity for diabetic vasculopathy

GP Fadini, S Sartore, M Albiero, I Baesso… - … , and vascular biology, 2006 - Am Heart Assoc
Objective—Peripheral arterial disease (PAD) is a threatening complication of diabetes. As
endothelial progenitor cells (EPCs) are involved in neovasculogenesis and maintenance of …

Unchain my heart: the scientific foundations of cardiac repair

S Dimmeler, AM Zeiher… - The Journal of clinical …, 2005 - Am Soc Clin Investig
In humans, the biological limitations to cardiac regenerative growth create both a clinical
imperative—to offset cell death in acute ischemic injury and chronic heart failure—and a …