Deep phenotyping of systemic arterial hemodynamics in HFpEF (part 2): clinical and therapeutic considerations

JA Chirinos - Journal of cardiovascular translational research, 2017 - Springer
Multiple phase III trials over the last few decades have failed to demonstrate a clear benefit
of various pharmacologic interventions in heart failure with a preserved left ventricular (LV) …

Arterial stiffness and pulsatile hemodynamics in heart failure

JA Chirinos - Textbook of Arterial Stiffness and Pulsatile …, 2022 - Elsevier
Arterial load exerts a profound impact on left ventricular structure and function. Assessments
of pulsatile arterial hemodynamics have provided important insights into the …

Extracerebral vascular contributions to brain aging and cognitive decline

LE DuBose - 2019 - search.proquest.com
The development of cognitive impairment including dementia is one of the major
contemporary healthcare crises of the current century. While the mechanism by which …