Recent advances in perioperative immunotherapies in lung cancer
S Fukuda, K Suda, A Hamada, Y Tsutani - Biomolecules, 2023 - mdpi.com
Several clinical trials have been revolutionizing the perioperative treatment of early-stage
non-small cell lung cancer (NSCLC). Many of these clinical trials involve cancer …
non-small cell lung cancer (NSCLC). Many of these clinical trials involve cancer …
Prognostic significance of STING expression in solid tumor: a systematic review and meta-analysis
Y Kim, NY Cho, L Jin, HY Jin, GH Kang - Frontiers in Oncology, 2023 - frontiersin.org
Objective Stimulator of interferon genes (STING) is a key regulator in initiating innate
immune response from sensing cytosolic DNA. Recent studies have revealed that the cGAS …
immune response from sensing cytosolic DNA. Recent studies have revealed that the cGAS …
The common H232 STING allele shows impaired activities in DNA sensing, susceptibility to viral infection, and in monocyte cell function, while the HAQ variant …
G Froechlich, A Finizio, A Napolano, S Amiranda… - Scientific Reports, 2023 - nature.com
Different innate immune pathways converge to Stimulator of interferon genes (STING) and
trigger type I interferon responses after recognition of abnormal nucleic acids in the cells …
trigger type I interferon responses after recognition of abnormal nucleic acids in the cells …
Protein expression of immune checkpoints STING and MHCII in small cell lung cancer
Background SCLC is an aggressive malignancy where immunotherapies show limited
efficacy. We aimed to characterize the SCLC microenvironment according to the expression …
efficacy. We aimed to characterize the SCLC microenvironment according to the expression …
Clinical significance of STING expression and methylation in lung adenocarcinoma based on bioinformatics analysis
Z Lin, Y Liu, P Lin, J Li, J Gan - Scientific Reports, 2022 - nature.com
The role of stimulator of interferon genes [STING, also known as transmembrane protein 173
(TMEM173)] in various human cancers has begun to emerge. However, the clinical value of …
(TMEM173)] in various human cancers has begun to emerge. However, the clinical value of …
Octadecyl Gallate and Lipid‐Modified MnSe2 Nanoparticles Enhance Radiosensitivity in Esophageal Squamous Cell Carcinoma and Promote Radioprotection in …
X Li, H Liu, W Gao, Q Yang, X Li, X Zhou… - Advanced …, 2024 - Wiley Online Library
Radiotherapy, a widely used therapeutic strategy for esophageal squamous cell carcinoma
(ESCC), is always limited by radioresistance of tumor tissues and side‐effects on normal …
(ESCC), is always limited by radioresistance of tumor tissues and side‐effects on normal …
Prognostic significance of STING immunoexpression in relation to HPV16 infection in patients with squamous cell carcinomas of oral cavity and oropharynx
B Biesaga, R Smolarczyk, A Mucha-Małecka, J Czapla… - Biomedicines, 2022 - mdpi.com
Infection with HPV16 in cancers of the oral cavity (OCSCC) and oropharynx (OPSCC) is,
today, an important etiological and prognostic factor. Patients with HPV-positive OPSCC …
today, an important etiological and prognostic factor. Patients with HPV-positive OPSCC …
Role of STING in the treatment of non-small cell lung cancer
W Tang, W Zhou, M Ji, X Yang - Cell Communication and Signaling, 2024 - Springer
Non-small cell lung cancer (NSCLC) is a prevalent form of lung cancer. Patients with
advanced NSCLC are currently being treated with various therapies, including traditional …
advanced NSCLC are currently being treated with various therapies, including traditional …
Stimulator of Interferon Genes Protein (STING) Expression in Cancer Cells: A Tissue Microarray Study Evaluating More than 18,000 Tumors from 139 Different Tumor …
A Menz, J Zerneke, F Viehweger, S Büyücek, D Dum… - Cancers, 2024 - mdpi.com
Stimulator of interferon genes protein (STING) activates the immune response in
inflammatory cells. STING expression in cancer cells is less well characterized, but STING …
inflammatory cells. STING expression in cancer cells is less well characterized, but STING …
STING expression is an independent prognostic factor in patients with mycosis fungoides
R Takayanagi-Hara, Y Sawada, H Sugino… - Scientific Reports, 2022 - nature.com
Mycosis fungoides is recognized as an indolent cutaneous malignant T-cell lymphoma. In
contrast, there are few therapeutic options for advanced forms of mycosis fungoides. Since …
contrast, there are few therapeutic options for advanced forms of mycosis fungoides. Since …