The Ku heterodimer: function in DNA repair and beyond
VL Fell, C Schild-Poulter - Mutation Research/Reviews in Mutation …, 2015 - Elsevier
Ku is an abundant, highly conserved DNA binding protein found in both prokaryotes and
eukaryotes that plays essential roles in the maintenance of genome integrity. In eukaryotes …
eukaryotes that plays essential roles in the maintenance of genome integrity. In eukaryotes …
[HTML][HTML] ELF3, ELF5, EHF and SPDEF transcription factors in tissue homeostasis and cancer
IY Luk, CM Reehorst, JM Mariadason - Molecules, 2018 - mdpi.com
The epithelium-specific ETS (ESE) transcription factors (ELF3, ELF5, EHF and SPDEF) are
defined by their highly conserved ETS DNA binding domain and predominant epithelial …
defined by their highly conserved ETS DNA binding domain and predominant epithelial …
Green tea polyphenol EGCG suppresses lung cancer cell growth through upregulating miR-210 expression caused by stabilizing HIF-1α
H Wang, S Bian, CS Yang - Carcinogenesis, 2011 - academic.oup.com
Epigallocatechin-3-gallate (EGCG) has been reported to affect many cellular regulatory
pathways. This study aims to determine whether EGCG could target microRNA (miRNA) …
pathways. This study aims to determine whether EGCG could target microRNA (miRNA) …
Conditional knockout mice reveal distinct functions for the global transcriptional coactivators CBP and p300 in T-cell development
LH Kasper, T Fukuyama, MA Biesen… - … and cellular biology, 2006 - Taylor & Francis
The global transcriptional coactivators CREB-binding protein (CBP) and the closely related
p300 interact with over 312 proteins, making them among the most heavily connected hubs …
p300 interact with over 312 proteins, making them among the most heavily connected hubs …
Foxs and Ets in the transcriptional regulation of endothelial cell differentiation and angiogenesis
E Dejana, A Taddei, AM Randi - … et Biophysica Acta (BBA)-Reviews on …, 2007 - Elsevier
During tumour growth the surrounding vasculature forms new vessels which penetrate into
the stroma and bring oxygen and nutrients to the proliferating cancer cells. The ability to …
the stroma and bring oxygen and nutrients to the proliferating cancer cells. The ability to …
[HTML][HTML] WTAP mediated N6-methyladenosine RNA modification of ELF3 drives cellular senescence by upregulating IRF8
L Zhou, Y Zhong, F Wang, Y Guo, R Mao… - … Journal of Biological …, 2024 - ncbi.nlm.nih.gov
Abstract N6-methyladenosine (m6A), the most prevalent posttranscriptional RNA
modification, involved in various diseases and cellular processes. However, the underlying …
modification, involved in various diseases and cellular processes. However, the underlying …
Regulation of vascular inflammation and remodeling by ETS factors
P Oettgen - Circulation research, 2006 - Am Heart Assoc
The ETS (E 26 T ransformation-specific S equence) factors are comprised of a family of
transcription factors that share a highly conserved DNA binding domain. Although originally …
transcription factors that share a highly conserved DNA binding domain. Although originally …
One ring to bring them all—the role of Ku in mammalian non-homologous end joining
The repair of DNA double strand breaks is essential for cell survival and several conserved
pathways have evolved to ensure their rapid and efficient repair. The non-homologous end …
pathways have evolved to ensure their rapid and efficient repair. The non-homologous end …
[HTML][HTML] Multiple roles of the epithelium-specific ETS transcription factor, ESE-1, in development and disease
The E26 transformation-specific (ETS) family of transcription factors comprises of 27 and 26
members in humans and mice, respectively, which are known to regulate many different …
members in humans and mice, respectively, which are known to regulate many different …
HLA-C expression in extravillous trophoblasts is determined by an ELF3–NLRP2/NLRP7 regulatory axis
The distinct human leukocyte antigen (HLA) class I expression pattern of human extravillous
trophoblasts (EVT) endows them with unique tolerogenic properties that enable successful …
trophoblasts (EVT) endows them with unique tolerogenic properties that enable successful …