Host defence peptides (HDPs) are integral components of innate immunity across all living
organisms. These peptides can exert direct antibacterial effects, targeting planktonic cells …

Antimicrobial peptides (AMPs) or host defense peptides protect the host against various
pathogens such as yeast, fungi, viruses and bacteria. AMPs also display immunomodulatory …

Staphylococcus aureus is capable of becoming resistant to all classes of antibiotics clinically
available and resistance can develop through de novo mutations in chromosomal genes or …

Staphylococcus aureus has been an exceptionally successful pathogen, which is still
relevant in modern age-medicine due to its adaptability and tenacity. This bacterium may be …

Peptide-based supramolecular assemblies are a promising class of nanomaterials with
important biomedical applications, specifically in drug delivery and tissue regeneration …

As more antibiotics are rendered ineffective by drug-resistant bacteria, focus must be shifted
towards alternative therapies for treating infections. Although several alternatives already …

The discovery of antibiotics has long been regarded as one of the most significant medical
achievements of the twentieth century. Antibiotics have saved millions of lives (1) and …

Most pharmaceutical companies have stopped or have severely limited investments to
discover and develop new antibiotics to treat the increasing prevalence of infections caused …

Currently, infections caused by drug-resistant bacteria have become a new challenge in anti-
infective treatment, seriously endangering public health. In our continuous effort to develop …

The public view on antibiotics as reliable medicines changed when reports about “resistant
superbugs” appeared in the news. While reasons for this resistance development are easily …