Cells are able to execute apoptosis by activating series of specific biochemical reactions.
One of the most prominent characteristics of cell death is the externalization of …

Plaque rupture and subsequent thrombotic occlusion of the coronary artery account for as
many as three quarters of myocardial infarctions. The concept of plaque stabilisation …

Objectives Statins have been shown to reduce plaque progression using data on
intravascular ultrasound, carotid intima-media thickness and coronary artery calcium scans …

Objectives: This study sought to assess, by serial computed tomography angiography (CTA),
the effect of statin treatment on coronary plaque morphology. Background: In addition to the …

Objective—Matrix metalloproteinase (MMP)-12 has been implicated in plaque progression
and instability and is also amenable to selective inhibition. In this study, we investigated the …

Apoptosis and macrophage burden are believed to correlate with atherosclerotic plaque
vulnerability and are therefore considered important diagnostic and therapeutic targets for …

Annexin V recognizes apoptotic cells by specific molecular interaction with phosphatidyl
serine, a lipid that is normally sequestered in the inner leaflet of the cell membrane, but is …

Atherosclerosis has been classified as the biggest health-care issue around the world1).
Indeed, global health statistics have shown that atherosclerotic cardiovascular disease is the …

As a major receptor for oxidized low density lipoprotein (ox-LDL), lectin-like oxidized low-
density lipoprotein receptor-1 (LOX-1) is upregulated in many pathophysiological events …

Cell death is desirable in cancer cells and undesirable in organs with limited regenerative
potential, like the heart. Cell death comes in many forms, but only apoptosis and to a lesser …