A turbulent decade for NSAIDs: update on current concepts of classification, epidemiology, comparative efficacy, and toxicity
PG Conaghan - Rheumatology international, 2012 - Springer
Non-steroidal anti-inflammatory drugs (NSAIDs) represent a diverse class of drugs and are
among the most commonly used analgesics for arthritic pain worldwide, though long-term …
among the most commonly used analgesics for arthritic pain worldwide, though long-term …
Adverse effects of cyclooxygenase 2 inhibitors on renal and arrhythmia events: meta-analysis of randomized trials
ContextAdverse effects of selective cyclooxygenase 2 (COX-2) inhibitors on renal events
and arrhythmia have been controversial, with suggestions of a class effect. ObjectiveTo …
and arrhythmia have been controversial, with suggestions of a class effect. ObjectiveTo …
Gastrointestinal safety of cyclooxygenase-2 inhibitors: a Cochrane Collaboration systematic review
A Rostom, K Muir, C Dubé, E Jolicoeur… - Clinical …, 2007 - Elsevier
Background & Aims: Nonselective non-steroidal anti-inflammatory drugs (NSAIDs) and
cyclooxygenase-2 inhibitors (COX-2s) are used to treat a variety of arthritic and inflammatory …
cyclooxygenase-2 inhibitors (COX-2s) are used to treat a variety of arthritic and inflammatory …
Evaluation of the efficacy of etoricoxib in ankylosing spondylitis: results of a fifty‐two–week, randomized, controlled study
D van der Heijde, HSB Baraf… - Arthritis & …, 2005 - Wiley Online Library
Objective To assess the efficacy, safety, and tolerability of etoricoxib, a cyclooxygenase 2
(COX‐2) selective inhibitor, administered continuously over 52 weeks for the treatment of …
(COX‐2) selective inhibitor, administered continuously over 52 weeks for the treatment of …
Clinical use and pharmacological properties of selective COX-2 inhibitors
S Shi, U Klotz - European journal of clinical pharmacology, 2008 - Springer
Abstract Selective COX-2 inhibitors (coxibs) are approved for the relief of acute pain and
symptoms of chronic inflammatory conditions such as osteoarthritis (OA) and rheumatoid …
symptoms of chronic inflammatory conditions such as osteoarthritis (OA) and rheumatoid …
Nonsteroidal anti-inflammatory drugs and hepatic toxicity: a systematic review of randomized controlled trials in arthritis patients
A Rostom, L Goldkind, L Laine - Clinical Gastroenterology and Hepatology, 2005 - Elsevier
Background & Aims: Nonsteroidal anti-inflammatory drugs (NSAIDs) might cause hepatic
side effects, but the frequency of these laboratory and clinical side effects is uncertain …
side effects, but the frequency of these laboratory and clinical side effects is uncertain …
Do COX-2 inhibitors raise blood pressure more than nonselective NSAIDs and placebo? An updated meta-analysis
Background Both COX-2 selective inhibitors (coxibs) and nonselective (ns)-NSAIDs elevate
blood pressure (BP) and this may contribute to excess cardiovascular (CV) events. A …
blood pressure (BP) and this may contribute to excess cardiovascular (CV) events. A …
Are all oral COX‐2 selective inhibitors the same? A consideration of celecoxib, etoricoxib, and diclofenac
C Walker - International journal of rheumatology, 2018 - Wiley Online Library
Nonsteroidal anti‐inflammatory drugs (NSAIDs) have been widely used for the treatment of
arthritic conditions. Drugs in this heterogeneous class alleviate pain and inflammation by …
arthritic conditions. Drugs in this heterogeneous class alleviate pain and inflammation by …
Definition of nonresponse to analgesic treatment of arthritic pain: an analytical literature review of the smallest detectable difference, the minimal detectable change …
ME Stauffer, SD Taylor, DJ Watson… - International journal …, 2011 - Wiley Online Library
Our objective was to develop a working definition of nonresponse to analgesic treatment of
arthritis, focusing on the measurement of pain on the 0–100 mm pain visual analog scale …
arthritis, focusing on the measurement of pain on the 0–100 mm pain visual analog scale …
COX-2 selective inhibitors in the treatment of osteoarthritis
L Laine, WB White, A Rostom, M Hochberg - Seminars in arthritis and …, 2008 - Elsevier
OBJECTIVES: To assess the efficacy of cyclooxygenase-2 selective inhibitors (coxibs) in
osteoarthritis (OA) and their gastrointestinal, cardiovascular, renovascular, and hepatic side …
osteoarthritis (OA) and their gastrointestinal, cardiovascular, renovascular, and hepatic side …