Keap1 (Kelch-like ECH-associated protein 1) is one of the major negative regulators of the
transcription factor Nrf2 (nuclear factor erythroid-2-related factor 2), which induces the …

The “amyloid cascade” hypothesis of Alzheimer's disease (AD) pathogenesis invokes the
accumulation in the brain of plaques (containing the amyloid-β protein precursor [AβPP] …

Background It is generally accepted that most evolutionary transformations at the phenotype
level are associated either with rearrangements of genomic regulatory elements, which …

From the evolutionary point of view, the priority problem for an individual is not longevity, but
adaptation to the environment associated with the need for survival, food supply, and …

Simple Summary The relationship between genomic characteristics and species traits is of
paramount importance for biology. For genomic characteristics, we considered …

The use of simple demographic indicators to describe mortality dynamics can obscure
important features of the survival curve, particularly during periods of rapid change, such as …

An original bioinformatics technique is developed to identify the protein-coding genes in
rodents, lagomorphs and nonhuman primates that are pseudogenized in humans. The …

The use of simple demographic indicators to describe mortality dynamics can obscure
important features of the survival curve, particularly during periods of rapid change, such as …

Биоритмы имеют важное адаптивное значение. Нарушение регуляции циркадных
ритмов-одно из характерных возрастных расстройств. Мы показали, что ген Fbxl21 …