The effect of metal ions (Fe, Co, Ni, and Cu) on the molecular-structural, protein binding, and cytotoxic properties of metal pyridoxal-thiosemicarbazone complexes

V Jevtovic, AK Alshamari, D Milenković… - International journal of …, 2023 - mdpi.com
Thiosemicarbazones and their transition metal complexes are biologically active
compounds and anticancer agents with versatile structural properties. In this contribution …

[HTML][HTML] Characterizing the binding interaction between antimalarial artemether (AMT) and bovine serum albumin (BSA): Spectroscopic and molecular docking …

J Shi, D Pan, X Wang, TT Liu, M Jiang… - Journal of Photochemistry …, 2016 - Elsevier
Artemether (AMT), a peroxide sesquiterpenoides, has been widely used as an antimalarial
for the treatment of multiple drug-resistant strains of plasmodium falciparum malaria. In this …

Studies on DNA binding properties of new Schiff base ligands using spectroscopic, electrochemical and computational methods: Influence of substitutions on DNA …

A Jamshidvand, M Sahihi, V Mirkhani… - Journal of Molecular …, 2018 - Elsevier
In this work, five new Schiff base ligands were synthesized and characterized by 1 H NMR,
13 C NMR, FT-IR, UV–Vis and elemental analysis (CHN). L 1, L 2 and L 3, were derived …

Silver‐Based Terpyridine Complexes as Antitumor Agents

M Gil‐Moles, ME Olmos, M Monge… - … A European Journal, 2023 - Wiley Online Library
Silver complexes bearing substituted terpyridine or tetra‐2‐pyridinylpyrazine ligands have
been prepared and structurally characterised. The study of the anticancer properties of silver …

Structural-dependent N, O-donor imine-appended Cu (II)/Zn (II) complexes: Synthesis, spectral, and in vitro pharmacological assessment

H Kabeer, S Hanif, A Arsalan, S Asmat, H Younus… - ACS …, 2020 - ACS Publications
Four mononuclear bioefficient imine-based coordination complexes,[(L 1) 2 Cu],[(L 1) 2
Zn],[(L 2) Cu (H 2 O)], and [(L 2) Zn (H 2 O)], were synthesized using ligands [L 1= 2-(((3 …

A water-soluble Pd (II) complex with a terpyridine ligand: experimental and molecular modeling studies of the interaction with DNA and BSA; and in vitro cytotoxicity …

F Darabi, H Hadadzadeh, J Simpson… - New Journal of …, 2016 - pubs.rsc.org
A new Pd (II) complex,[Pd (4-OHPh-tpy) Cl] Cl, with a ligand that is a terpyridine
derivative,(4′-(4-hydroxyphenyl)-2, 2′, 6′, 2′′-terpyridine (4-OHPh-tpy)), was …

Quenching Studies as Important Toolkit for Exploring Binding Propensity of Metal Complexes with Serum Albumin and DNA (A Review)

A Saini, P Bansal - Pharmaceutical Chemistry Journal, 2022 - Springer
Coordination complexes have played an important role in medicine since ancient times;
recently their pharmacological activity has been the subject of utmost interest. In this context …

Homoleptic metal complexes derived from hydrazones as ligand; synthesis, cytotoxic activity, photoluminescence properties and ADMET studies

AO Sarıoğlu, Z Bulut, DT Kahraman, S Güler… - Journal of Molecular …, 2024 - Elsevier
In the present work, N'-(2‑hydroxy-5-nitrobenzylidene) thiophene-2-carbohydrazide (L) and
its Cu (II), Ni (II), Co (II), and Fe (II) complexes have been prepared. Their chemical …

Synthesis, characterization, crystal structure, DNA-and HSA-binding studies of a dinuclear Schiff base Zn (II) complex derived from 2-hydroxynaphtaldehyde and 2 …

Z Kazemi, HA Rudbari, V Mirkhani, M Sahihi… - Journal of Molecular …, 2015 - Elsevier
A tridentate Schiff base ligand NNO donor (HL: 1-((E)-((pyridin-2-yl) methylimino) methyl)
naphthalen-2-ol was synthesized from condensation of 2-hydroxynaphtaldehyde and 2 …

Effect of a metal Ion in modulating the binding interaction of a dietary flavonoid with bovine serum albumin and DNA: a spectroscopic and theoretical approach

P Sengupta, U Pal, P Roy, T Samanta… - ACS Food Science & …, 2022 - ACS Publications
Plant-derived flavonoids are an excellent option as a potential substitute to synthetic
products in food industries, and flavonoid–metal complexes exhibit better functional …