Mechanisms of injury to normal tissue after radiotherapy: a review

JR Hubenak, Q Zhang, CD Branch… - Plastic and …, 2014 - journals.lww.com
Background: The benefits of radiotherapy for cancer have been well documented for many
years, but many patients treated with radiation develop adverse effects. This study analyzed …

Recent progress of astatine-211 in endoradiotherapy: Great advances from fundamental properties to targeted radiopharmaceuticals

F Li, Y Yang, J Liao, N Liu - Chinese Chemical Letters, 2022 - Elsevier
Abstract Astatine-211 (211 At, t 1/2= 7.21 h) emitting two α particles with energies of 5.87
and 7.45 MeV, can lead to a high linear energy transfer (LET= 98.84 keV/µm) and short …

Single-cell analysis of the ventricular-subventricular zone reveals signatures of dorsal and ventral adult neurogenesis

A Cebrian-Silla, MA Nascimento, SA Redmond… - Elife, 2021 - elifesciences.org
The ventricular-subventricular zone (V-SVZ), on the walls of the lateral ventricles, harbors
the largest neurogenic niche in the adult mouse brain. Previous work has shown that neural …

DNA damage by radiopharmaceuticals and mechanisms of cellular repair

Y Khazaei Monfared, P Heidari, SJ Klempner… - Pharmaceutics, 2023 - mdpi.com
DNA is an organic molecule that is highly vulnerable to chemical alterations and breaks
caused by both internal and external factors. Cells possess complex and advanced …

Effect of Low Doses (5-40 cGy) of Gamma-irradiation on Lifespan and Stress-related Genes Expression Profile in Drosophila melanogaster

S Zhikrevetskaya, D Peregudova, A Danilov… - PloS one, 2015 - journals.plos.org
Studying of the effects of low doses of γ-irradiation is a crucial issue in different areas of
interest, from environmental safety and industrial monitoring to aerospace and medicine …

Gene Expression Response of Mice after a Single Dose of 137Cs as an Internal Emitter

S Paul, SA Ghandhi, W Weber… - Radiation …, 2014 - meridian.allenpress.com
Cesium-137 is a radionuclide of concern in fallout from reactor accidents or nuclear
detonations. When ingested or inhaled, it can expose the entire body for an extended period …

Radiation dose-rate effects on gene expression in a mouse biodosimetry model

S Paul, LB Smilenov, CD Elliston… - Radiation …, 2015 - meridian.allenpress.com
In the event of a nuclear accident or radiological terrorist attack, there will be a pressing
need for biodosimetry to triage a large, potentially exposed population and to assign …

[PDF][PDF] Radionuclides in radiation-induced bystander effect; may it share in radionuclide therapy

M Widel - Neoplasma, 2017 - researchgate.net
For many years in radiobiology and radiotherapy predominated the conviction that cellular
DNA is the main target for ionizing radiation, however, the view has changed in the past 20 …

Endogenous neural stem cells characterization using omics approaches: Current knowledge in health and disease

V Murtaj, E Butti, G Martino… - Frontiers in Cellular …, 2023 - frontiersin.org
Neural stem cells (NSCs), an invaluable source of neuronal and glial progeny, have been
widely interrogated in the last twenty years, mainly to understand their therapeutic potential …

Age and sex effects across the blood proteome after ionizing radiation exposure can bias biomarker screening and risk assessment

B Langen, E Vorontsov, J Spetz, J Swanpalmer… - Scientific Reports, 2022 - nature.com
Molecular biomarkers of ionizing radiation (IR) exposure are a promising new tool in various
disciplines: they can give necessary information for adaptive treatment planning in cancer …