[HTML][HTML] Integration strategy of network pharmacology in Traditional Chinese Medicine: a narrative review

WU Jiashuo, F ZHANG, LI Zhuangzhuang… - Journal of Traditional …, 2022 - ncbi.nlm.nih.gov
Abstract Traditional Chinese Medicine (TCM) has been extensively used as a mainstay for
treating various pathologies. Combing the pharmacology and systems biology approaches …

Systems pharmacology for investigation of the mechanisms of action of traditional Chinese medicine in drug discovery

W Zhang, Y Huai, Z Miao, A Qian… - Frontiers in pharmacology, 2019 - frontiersin.org
As a traditional medical intervention in Asia and a complementary and alternative medicine
in western countries, traditional Chinese medicine (TCM) has attracted global attention in …

In silico polypharmacology of natural products

J Fang, C Liu, Q Wang, P Lin… - Briefings in bioinformatics, 2018 - academic.oup.com
Natural products with polypharmacological profiles have demonstrated promise as novel
therapeutics for various complex diseases, including cancer. Currently, many gaps exist in …

Compound-based Chinese medicine formula: From discovery to compatibility mechanism

X Luan, LJ Zhang, XQ Li, K Rahman, H Zhang… - Journal of …, 2020 - Elsevier
Ethnopharmacological relevance Chinese medicine formula (CMF) has a long history of
clinical use in the treatment of various diseases under the guidance of traditional Chinese …

[HTML][HTML] Drug databases and their contributions to drug repurposing

Y Masoudi-Sobhanzadeh, Y Omidi, M Amanlou… - Genomics, 2020 - Elsevier
Drug repurposing is an interesting field in the drug discovery scope because of reducing
time and cost. It is also considered as an appropriate method for finding medications for …

Phytochemicals based chemopreventive and chemotherapeutic strategies and modern technologies to overcome limitations for better clinical applications

VK Singh, D Arora, MI Ansari… - Phytotherapy …, 2019 - Wiley Online Library
Naturally occurring phytochemicals or plant derivatives are now being explored extensively
for their health's benefits and medicinal uses. The therapeutic effect of phytochemicals has …

Plant metabolite databases: from herbal medicines to modern drug discovery

TH Nguyen-Vo, L Nguyen, N Do… - Journal of chemical …, 2019 - ACS Publications
Traditional herbal medicine has been an inseparable part of the traditional medical science
in many countries throughout history. Nowadays, the popularity of using herbal medicines in …

Recent advances in the area of plant-based anti-cancer drug discovery using computational approaches

AP Das, SM Agarwal - Molecular Diversity, 2024 - Springer
Phytocompounds are a well-established source of drug discovery due to their unique
chemical and functional diversities. In the area of cancer therapeutics, several …

Methodology of network pharmacology for research on Chinese herbal medicine against COVID-19: A review

Y Wang, Z Yang, W Wang, Y Huang, Q Zhang… - Journal of integrative …, 2022 - Elsevier
Traditional Chinese medicine, as a complementary and alternative medicine, has been
practiced for thousands of years in China and possesses remarkable clinical efficacy. Thus …

iANP-EC: identifying anticancer natural products using ensemble learning incorporated with evolutionary computation

L Nguyen, TH Nguyen Vo, QH Trinh… - Journal of Chemical …, 2022 - ACS Publications
Cancer is one of the most deadly diseases that annually kills millions of people worldwide.
The investigation on anticancer medicines has never ceased to seek better and more …