Therapeutic potential of cannabis: a comprehensive review of current and future applications
ZJ Leinen, R Mohan, LS Premadasa, A Acharya… - Biomedicines, 2023 - mdpi.com
Historically, cannabis has been valued for its pain-relieving, anti-inflammatory, and calming
properties. Ancient civilizations like the Egyptians, Greeks, and Chinese medicines …
properties. Ancient civilizations like the Egyptians, Greeks, and Chinese medicines …
Cannabinoid treatments in epilepsy and seizure disorders
O Devinsky, NA Jones, MO Cunningham… - Physiological …, 2024 - journals.physiology.org
Cannabis has been used to treat convulsions and other disorders since ancient times. In the
last few decades, preclinical animal studies and clinical investigations have established the …
last few decades, preclinical animal studies and clinical investigations have established the …
Structure–Activity Relationship Study of Cannabidiol-Based Analogs as Negative Allosteric Modulators of the μ-Opioid Receptor
T Bosquez-Berger, JA Gudorf, CP Kuntz… - Journal of Medicinal …, 2023 - ACS Publications
The US faces an unprecedented surge in fatal drug overdoses. Naloxone, the only antidote
for opiate overdose, competes at the mu opioid receptor (μOR) orthosteric site. Naloxone …
for opiate overdose, competes at the mu opioid receptor (μOR) orthosteric site. Naloxone …
Presynaptic nanoscale components of retrograde synaptic signaling
While our understanding of the nanoscale architecture of anterograde synaptic transmission
is rapidly expanding, the qualitative and quantitative molecular principles underlying distinct …
is rapidly expanding, the qualitative and quantitative molecular principles underlying distinct …
GKLF, a transcriptional activator of Txnip, drives microglia activation in kainic acid-induced murine models of epileptic seizures
Z Zhuo, Y Wang, H Kong, T Fu - International Immunopharmacology, 2023 - Elsevier
Neuroinflammation is a major component of epilepsy. Gut-enriched Kruppel-like factor
(GKLF), a transcription factor of Kruppel-like factor family, has been reported to promote …
(GKLF), a transcription factor of Kruppel-like factor family, has been reported to promote …
Restoring prefrontal cortical excitation-inhibition balance with cannabidiol ameliorates neurobehavioral abnormalities in a mouse model of neurodevelopmental …
L Zhang, C Lin, J Zhu, Y He, M Zhan, X Xia, N Yang… - …, 2023 - Elsevier
Maternal immune activation (MIA) resulting from viral infections during pregnancy is linked to
increased rates of neurodevelopmental disorders in offspring. However, the mechanisms …
increased rates of neurodevelopmental disorders in offspring. However, the mechanisms …
The development of cannabinoids as therapeutic agents in the United States
Cannabis is one of the oldest and widely used substances in the world. Cannabinoids within
the cannabis plant, known as phytocannabinoids, mediate cannabis9 effects through …
the cannabis plant, known as phytocannabinoids, mediate cannabis9 effects through …
Adaptive deep spiking neural network with global-local learning via balanced excitatory and inhibitory mechanism
The training method of Spiking Neural Networks (SNNs) is an essential problem, and how to
integrate local and global learning is a worthy research interest. However, the current …
integrate local and global learning is a worthy research interest. However, the current …
[HTML][HTML] Ameliorative effect of Nyctanthes arbor-tristis L. by suppression of pentylenetetrazole-induced kindling in mice: An insight from EEG, neurobehavioral and in …
Epilepsy is an abiding condition associated with recurrent seizure attacks along with
associated neurological and psychological emanation owing to disparity of excitatory and …
associated neurological and psychological emanation owing to disparity of excitatory and …
Activation of GPR55 Ameliorates Maternal Separation-Induced Learning and Memory Deficits by Augmenting 5-HT Synthesis in the Dorsal Raphe Nucleus of Juvenile …
T Sun, YY Du, YQ Zhang, QQ Tian, X Li, JY Yu… - ACS …, 2024 - ACS Publications
Maternal separation (MS) represents a profound early life stressor with enduring impacts on
neuronal development and adult cognitive function in both humans and rodents. MS is …
neuronal development and adult cognitive function in both humans and rodents. MS is …