[HTML][HTML] Long-acting microneedle formulations

LK Vora, AH Sabri, Y Naser, A Himawan… - Advanced Drug Delivery …, 2023 - Elsevier
The minimally-invasive and painless nature of microneedle (MN) application has enabled
the technology to obviate many issues with injectable drug delivery. MNs not only administer …

Microneedles: a new frontier in nanomedicine delivery

E Larrañeta, MTC McCrudden, AJ Courtenay… - Pharmaceutical …, 2016 - Springer
This review aims to concisely chart the development of two individual research fields,
namely nanomedicines, with specific emphasis on nanoparticles (NP) and microparticles …

Microneedles for intradermal and transdermal drug delivery

TM Tuan-Mahmood, MTC McCrudden… - European Journal of …, 2013 - Elsevier
The formidable barrier properties of the uppermost layer of the skin, the stratum corneum,
impose significant limitations for successful systemic delivery of broad range of therapeutic …

A review of the structure, preparation, and application of NLCs, PNPs, and PLNs

Q Li, T Cai, Y Huang, X Xia, SPC Cole, Y Cai - Nanomaterials, 2017 - mdpi.com
Nanostructured lipid carriers (NLCs) are modified solid lipid nanoparticles (SLNs) that retain
the characteristics of the SLN, improve drug stability and loading capacity, and prevent drug …

Absorption, distribution, metabolism and excretion of the biomaterials used in Nanocarrier drug delivery systems

C Su, Y Liu, R Li, W Wu, JP Fawcett, J Gu - Advanced drug delivery reviews, 2019 - Elsevier
Nanocarriers (NCs) are a type of drug delivery system commonly used to regulate the
pharmacokinetic and pharmacodynamic properties of drugs. Although a wide variety of NCs …

Polymeric nanoparticles‐based topical delivery systems for the treatment of dermatological diseases

Z Zhang, PC Tsai, T Ramezanli… - Wiley Interdisciplinary …, 2013 - Wiley Online Library
Human skin not only functions as a permeation barrier (mainly because of the stratum
corneum layer) but also provides a unique delivery pathway for therapeutic and other active …

Transdermal delivery systems for biomolecules

MC Peña-Juárez, OR Guadarrama-Escobar… - Journal of …, 2021 - Springer
Purpose The present review article focuses on highlighting the main technologies used as
tools that improve the delivery of transdermal biomolecules, addressing them from the point …

Nanoparticles-encapsulated polymeric microneedles for transdermal drug delivery

M Chen, G Quan, Y Sun, D Yang, X Pan… - Journal of Controlled …, 2020 - Elsevier
Polymeric microneedles (MNs) have been leveraged as a novel transdermal drug delivery
platform for effective drug permeation, which were widely used in the treatment of various …

Dissolving polymer microneedle patches for rapid and efficient transdermal delivery of insulin to diabetic rats

MH Ling, MC Chen - Acta biomaterialia, 2013 - Elsevier
This study presents a dissolving microneedle patch, composed of starch and gelatin, for the
rapid and efficient transdermal delivery of insulin. The microneedles completely dissolve …

Micro electromechanical systems (MEMS) based microfluidic devices for biomedical applications

MW Ashraf, S Tayyaba, N Afzulpurkar - International journal of molecular …, 2011 - mdpi.com
Micro Electromechanical Systems (MEMS) based microfluidic devices have gained
popularity in biomedicine field over the last few years. In this paper, a comprehensive …