Precision oncology continues to challenge the “one-size-fits-all” dogma. Under the precision
oncology banner, cancer patients are screened for molecular tumor alterations that predict …

To overcome the drawbacks of conventional delivery, this review spotlights a number of
nanoscale drug delivery systems, including nanoparticles, liposomes, nano micelles …

Solid tumors generate a suppressive environment that imposes an overwhelming burden on
the immune system. Nutrient depletion, waste product accumulation, hypoxia, and pH …

Organs-on-a-chip, or OoCs, are microfluidic tissue culture devices with micro-scaled
architectures that repeatedly achieve biomimicry of biological phenomena. They are well …

Every year, cancer claims millions of lives around the globe. Unfortunately, model systems
that accurately mimic human oncology–a requirement for the development of more effective …

Patient-derived cancer organoids have taken a prominent role in pre-clinical and
translational research and have been generated for most common solid tumors. Cancer …

Microfluidic lumen-based systems are microscale models that recapitulate the anatomy and
physiology of tubular organs. These technologies can mimic human pathophysiology and …

Advanced forms of hydrogels have many inherently desirable properties and can be
designed with different structures and functions. In particular, bioresponsive multifunctional …

Organ on chip (OOC) has emerged as a major technological breakthrough and distinct
model system revolutionizing biomedical research and drug discovery by recapitulating the …

Organoid models have been used to address important questions in developmental and
cancer biology, tissue repair, advanced modelling of disease and therapies, among other …