Toward complete rational control over protein structure and function through computational design

J Adolf-Bryfogle, FD Teets, CD Bahl - Current opinion in structural biology, 2021 - Elsevier
Highlights•The grand challenge of computational protein design is the generalized ability to
confer arbitrary functions and properties.•Protein shape, function and solution behavior are …

Competition and evolutionary selection among core regulatory motifs in gene expression control

A Gyorgy - Nature communications, 2023 - nature.com
Gene products that are beneficial in one environment may become burdensome in another,
prompting the emergence of diverse regulatory schemes that carry their own bioenergetic …

[图书][B] Single Cell Imaging in Yeast Reveals the Interplay Between Organelle Size Scaling and Proteosome Dynamics That Impacts Major Aging Hallmarks

M Mobaraki - 2023 - search.proquest.com
Aging is a risk factor for many diseases, and understanding the hallmarks of aging is crucial
for developing interventions to promote healthy aging. Despite the conservation of the aging …