[HTML][HTML] Advanced nanocarrier-and microneedle-based transdermal drug delivery strategies for skin diseases treatment

F Qu, R Geng, Y Liu, J Zhu - Theranostics, 2022 - ncbi.nlm.nih.gov
Skin diseases are the fourth leading cause of nonfatal and chronic skin diseases, acting as a
global burden and affecting the world economy. Skin diseases severely impact the patients' …

Cancer hallmarks define a continuum of plastic cell states between small cell lung cancer archetypes

SM Groves, A Ireland, Q Liu, AJ Simmons, K Lau… - BioRxiv, 2021 - biorxiv.org
Abstract Small Cell Lung Cancer (SCLC) tumors are heterogeneous mixtures of
transcriptional subtypes. Understanding subtype dynamics could be key to explaining the …

scGraph2Vec: a deep generative model for gene embedding augmented by graph neural network and single-cell omics data

S Lin, P Jia - GigaScience, 2024 - academic.oup.com
Background Exploring the cellular processes of genes from the aspects of biological
networks is of great interest to understanding the properties of complex diseases and …

RegVelo: gene-regulatory-informed dynamics of single cells

W Wang, Z Hu, P Weiler, S Mayes, M Lange, J Wang… - bioRxiv, 2024 - biorxiv.org
RNA velocity has emerged as a popular approach for modeling cellular change along the
phenotypic landscape but routinely omits regulatory interactions between genes …

SOX10 and microRNAs: decoding their interplay in regulating melanoma plasticity

X Lai, C Luan, Z Zhang, A Wessely, M Heppt, C Berking… - bioRxiv, 2024 - biorxiv.org
Recent studies show that the dysregulation of the transcription factor SOX10 is essential for
development and progression of melanoma. MicroRNAs (miRNAs) can regulate the …