Fluorinated prolines as conformational tools and reporters for peptide and protein chemistry

SJM Verhoork, PM Killoran, CR Coxon - Biochemistry, 2018 - ACS Publications
Amide bonds at the proline nitrogen are particularly susceptible to rotation, affording cis and
trans isomers. Installation of a stereochemically defined electron-withdrawing fluorine atom …

[图书][B] Development of New Synthetic Approaches to Biologically-Active Peptides

SJM Verhoork - 2019 - search.proquest.com
Synthetic peptides are widely used in drug research due to their high selectivity and
efficaciousness, as well as in chemical biology as tools for modulating protein-protein …