The heat shock proteins (HSPs) are ubiquitous and conserved protein families in both
prokaryotic and eukaryotic organisms, and they maintain cellular proteostasis and protect …

Among the long list of age-related complications, Alzheimer's disease (AD) has the most
dreadful impact on the quality of life due to its devastating effects on memory and cognitive …

Among diseases whose cure is still far from being discovered, Alzheimer's disease (AD) has
been recognized as a crucial medical and social problem. A major issue in AD research is …

Hsp90 is a highly abundant and ubiquitous molecular chaperone which plays an essential
role in many cellular processes including cell cycle control, cell survival, hormone and other …

Emerging evidence indicates that heat shock proteins (HSPs) are critical regulators in
normal neural physiological function as well as in cell stress responses. The functions of …

Introduction The blood-brain barrier (BBB) is damaged in tauopathies, including progressive
supranuclear palsy (PSP) and Alzheimer's disease (AD), which is thought to contribute to …

Neurodegenerative diseases are featured by progressive dysfunction and death of cells in
selected areas in the nervous system, determining clinical presentation. Neuronal loss is …

Alzheimer's disease (AD) is a common neurodegenerative disorder that affects the elderly.
One of the key features of AD is the accumulation of reactive oxygen species (ROS), which …

Identifying early-detection biomarkers have become an increasingly important approach in
the treatment and prevention of Alzheimer's disease (AD). In this study, we investigated the …

Rationale: It has been reported that peroxisome proliferator activated receptor γ (PPARγ)
level decreases significantly in the brains of Alzheimer's disease (AD) patients and mice …