The introduction of biologically relevant organic moieties in the coordination sphere of
transition metal complexes has recently become a well-established strategy to increase the …

Platinum complexes are used in chemotherapy, primarily as antineoplastic agents. In this
study, we assessed the cytotoxic and cytostatic properties of a set of osmium (II), ruthenium …

The current study shows the synthesis of reduced graphene incorporated ruthenium oxide
(rGO/RuO 2) using a reflux approach. The rGO/RuO 2 nanocomposite was confirmed using …

The toxicity of and resistance to platinum complexes as cisplatin, oxaliplatin or carboplatin
calls for the replacement of these therapeutic agents in clinical settings. We have previously …

Eight novel carbohydrate-tethered trithiolato dinuclear ruthenium (II)-arene complexes were
synthesized using CuAAC 'click'(Cu (I)-catalyzed azide-alkyne cycloaddition) reactions, and …

While platinum-based compounds such as cisplatin form the backbone of chemotherapy, the
use of these compounds is limited by resistance and toxicity, driving the development of …

A series of half-sandwich ruthenium complexes containing quinoline derivative ligands was
synthesized, which had excellent antitumor toxicity toward a variety of cell lines and could …

Glycoconjugation is a powerful tool to improve the anticancer activity of metal complexes.
Herein, we modified commercial arylphosphanes with carbohydrate-derived fragments for …

Bacterial resistance to antibiotics is an ever-growing problem in heathcare. We have
previously identified a set of osmium (II), ruthenium (II), iridium (III) and rhodium (III) half …

Nine ruthenium CNC pincer complexes (1–9) were tested for anticancer activity in cell
culture under both dark and light conditions. These complexes included varied CNC pincer …