Aging is a complex biological process accompanied by a progressive decline in the physical
function of the organism and an increased risk of age-related chronic diseases such as …

Aging is the greatest risk factor for a multitude of diseases including cardiovascular disease,
neurodegeneration and cancer. Despite decades of research dedicated to understanding …

Aging has been linked to several degenerative processes that, through the accumulation of
molecular and cellular damage, can progressively lead to cell dysfunction and organ failure …

Microplastic pollution has drawn the attention of both scientists and the public regarding
their potential ecotoxicological risks. In the present study, we carried out aqueous exposure …

Maximum life span differences among animal species exceed life span variation achieved
by experimental manipulation by orders of magnitude. The differences in the characteristic …

Bigger animals live longer. The scaling exponent for the relationship between lifespan and
body mass is between 0.15 and 0.3. Bigger animals also expend more energy, and the …

An updated version of the mitochondrial free radical theory of aging (MFRTA) and longevity
is reviewed. Key aspects of the theory are emphasized. Another main focus concerns …

Research programmes on oxidative stress and hormesis are wide ranging. Biomedical and
toxicological sciences have traditionally centralised such research, but in the last years we …

Sites of close contact between mitochondria and the endoplasmic reticulum (ER) are known
as mitochondria-associated membranes (MAM) or mitochondria-ER contacts (MERCs), and …

In this review, it is our aim 1) to describe the high diversity in molecular and structural
antioxidant defenses against oxidative stress in animals, 2) to extend the traditional concept …