Recently, mesenchymal stem/stromal cells (MSCs) and their widespread biomedical
applications have attracted great consideration from the scientific community around the …

Cell-based drug delivery systems (DDSs) have received attention recently because of their
unique biological properties and self-powered functions, such as excellent biocompatibility …

Almost every experimental treatment strategy using non-autologous cell, tissue or organ
transplantation is tested in small and large animal models before clinical translation …

Diabetic nephropathy (DN) is one of the most common microvascular complications of
diabetes and the leading cause of end-stage renal disease. The proliferation of glomerular …

Diabetes mellitus is a pandemic metabolic disorder that results from either the autoimmune
destruction or the dysfunction of insulin-producing pancreatic beta cells. A promising cure is …

Context Diabetes causes severe pathological changes to the microvasculature in many
organs and tissues and is at the same time associated with an increased risk of coronary …

Background Type 1 and Type 2 diabetes mellitus (T1DM and T2DM) are caused by beta (β)-
cell loss and functional impairment. Identification of mechanisms of β-cell death and …

Immunoisolation of pancreatic islets is a technology in which islets are encapsulated in
semipermeable but immunoprotective polymeric membranes. The technology allows for …

Natural killer cells (NK cells) are innate immune cells that are activated to fight tumor cells
and virus-infected cells. NK cells also play an important role in the graft versus leukemia …

Pro-inflammatory cytokines can effectively be used for tumor immunotherapy, affecting every
step of the tumor immunity cycle. Thereby, they can restore antigen priming, improve the …