Doxorubicin is a widely used and promising anticancer drug; however, a severe dose-
dependent cardiotoxicity hampers its therapeutic value. Doxorubicin may cause acute and …

Background Doxorubicin is one of the most commonly prescribed and time-tested anticancer
drugs. Although being considered as a first line drug in different types of cancers, the two …

Bacterial cellulose and gelatin were successfully used to develop a hydrogel composite
material. Hydrogel was synthesized by copolymerization between bacterial cellulose and …

Lapatinib (LAP) is an important anti-cancer drug and is frequently alongside doxorubicin
(DOX) as a combination therapy for better anti-cancer efficacy. However, many studies have …

Background: Doxorubicin (Dox) can induce endotheliotoxicity and damage the vascular
endothelium (VE). The most principle mechanism might be excess reactive oxygen species …

The second-most common cause of dementia is vascular dementia (VaD). The majority of
VaD patients experience cognitive impairment, which is brought on by oxidative stress and …

In the present study, we explored SA's activity against DOX‐induced cardiotoxicity and
revealed its underlying mechanisms. Male Wistar rats (weight, 190‐210g; n= 6) were …

Cardiotoxicity is a major side effect of the chemotherapeutic drug doxorubicin (Dox), which is
further exacerbated when it is combined with trastuzumab, a standard care approach for …

Doxorubicin (DOX) is an anthracycline chemotherapy drug used in the treatment of various
types of cancer. However, short-term and long-term cardiotoxicity limits the clinical …

Background: Doxorubicin (DOX), a broad-spectrum chemotherapy drug, is clinically
employed to treat cancers especially for breast cancer and lung cancer. But its clinical …