The immune nature of platelets revisited

A Maouia, J Rebetz, R Kapur, JW Semple - Transfusion medicine reviews, 2020 - Elsevier
Platelets are the primary cellular mediators of hemostasis and this function firmly acquaints
them with a variety of inflammatory processes. For example, platelets can act as circulating …

Inflammatory chemokines in atherosclerosis

S Gencer, BR Evans, EPC van der Vorst, Y Döring… - Cells, 2021 - mdpi.com
Atherosclerosis is a long-term, chronic inflammatory disease of the vessel wall leading to the
formation of occlusive or rupture-prone lesions in large arteries. Complications of …

Macrophage phenotypes in atherosclerosis

S Colin, G Chinetti‐Gbaguidi, B Staels - Immunological reviews, 2014 - Wiley Online Library
Initiation and progression of atherosclerosis depend on local inflammation and
accumulation of lipids in the vascular wall. Although many cells are involved in the …

Macrophage subsets in atherosclerosis

G Chinetti-Gbaguidi, S Colin, B Staels - Nature Reviews Cardiology, 2015 - nature.com
Macrophage accumulation within the vascular wall is a hallmark of atherosclerosis. In
atherosclerotic lesions, macrophages respond to various environmental stimuli, such as …

Emerging roles for platelets as immune and inflammatory cells

CN Morrell, AA Aggrey, LM Chapman… - Blood, The Journal of …, 2014 - ashpublications.org
Despite their small size and anucleate status, platelets have diverse roles in vascular
biology. Not only are platelets the cellular mediator of thrombosis, but platelets are also …

Macrophage subsets in atherosclerosis as defined by single‐cell technologies

L Willemsen, MPJ de Winther - The Journal of pathology, 2020 - Wiley Online Library
Macrophages play a major role in the pathogenesis of atherosclerosis. Many studies have
shone light on the different phenotypes and functions that macrophages can acquire upon …

Platelet-derived chemokines in inflammation and atherosclerosis

C Bakogiannis, M Sachse, K Stamatelopoulos… - Cytokine, 2019 - Elsevier
Platelets are inflammatory anuclear cells with a well-established role in the development
and manifestation of atherosclerosis. Activated platelets secrete a plethora of chemokines …

Atherosclerosis, platelets and thrombosis in acute ischaemic heart disease

L Badimon, T Padró, G Vilahur - European Heart Journal: Acute …, 2012 - academic.oup.com
Atherosclerosis is the underlying reason for nearly all causes of coronary artery disease and
peripheral arterial disease and many cases of stroke. Atherosclerosis is a systemic …

Platelet activation and atherothrombosis

G Davì, C Patrono - New England Journal of Medicine, 2007 - Mass Medical Soc
This review of the role of platelets in atherothrombosis illuminates the surprisingly numerous
activities of these tiny, anucleate cells and stresses their participation in the inflammatory …

Platelets in inflammation and atherogenesis

M Gawaz, H Langer, AE May - The Journal of clinical …, 2005 - Am Soc Clin Investig
Platelets represent an important linkage between inflammation, thrombosis, and
atherogenesis. Inflammation is characterized by interactions among platelets, leukocytes …