DNA has been a key target for cancer therapy, with a range of compounds able to bind and
either impair its processing or induce damage. Targeting DNA with small molecules in a truly …

The global issue of antimicrobial resistance poses significant challenges to public health.
The World Health Organization (WHO) has highlighted it as a major global health threat …

Staphylococcus aureus is a common cause of both superficial and invasive infections of
humans and animals. Despite a potent host response and apparently appropriate antibiotic …

Tuberculosis is the leading cause of mortality by infectious agents worldwide. The necrotic
debris, known as caseum, which accumulates in the center of pulmonary lesions and …

DNA double-strand breaks (DSBs), marked by ionizing radiation-induced (repair) foci
(IRIFs), are the most serious DNA lesions and are dangerous to human health. IRIF …

Umbilical cord mesenchymal stem cell-derived extracellular vesicles (UC-EVs) are valuable
in nanomedicine as natural nanocarriers, carrying information molecules from their parent …

Synthetic biology holds great promise for translating ideas into products to address the
grand challenges facing humanity. Molecular biomanufacturing is an emerging technology …

Aim: A bacterial genetics-guided approach was utilized for the discovery of new compounds
affecting bacterial genome stability. Materials & methods: Fungal extracts and fractions were …

UvrD is a multi-functional Escherichia coli helicase. It is widely involved in DNA repair,
including its DNA unwinding role during mismatch repair and RNAP removal role during …

Природные цеолиты эффективно используются в качестве удобрений, субстратов и
носителей для пестицидов, а также сорбентов при восстановлении загрязненных почв …