Macrophages: versatile players in renal inflammation and fibrosis

PMK Tang, DJ Nikolic-Paterson, HY Lan - Nature Reviews Nephrology, 2019 - nature.com
Macrophages have important roles in immune surveillance and in the maintenance of
kidney homeostasis; their response to renal injury varies enormously depending on the …

Pathogenic pathways and therapeutic approaches targeting inflammation in diabetic nephropathy

S Rayego-Mateos, JL Morgado-Pascual… - International journal of …, 2020 - mdpi.com
Diabetic nephropathy (DN) is associated with an increased morbidity and mortality, resulting
in elevated cost for public health systems. DN is the main cause of chronic kidney disease …

[HTML][HTML] Diabetes and cardiovascular disease: epidemiology, biological mechanisms, treatment recommendations and future research

BM Leon, TM Maddox - World journal of diabetes, 2015 - ncbi.nlm.nih.gov
The incidence of diabetes mellitus (DM) continues to rise and has quickly become one of the
most prevalent and costly chronic diseases worldwide. A close link exists between DM and …

Mechanisms of antidiabetic effects of flavonoid rutin

A Ghorbani - Biomedicine & Pharmacotherapy, 2017 - Elsevier
Several lines of evidence suggest that flavonoids that originated from vegetables and
medicinal plants have beneficial effects on diabetes by improving glycemic control, lipid …

Pathophysiologic mechanisms in diabetic kidney disease: A focus on current and future therapeutic targets

J Barrera‐Chimal, F Jaisser - Diabetes, Obesity and …, 2020 - Wiley Online Library
Diabetic kidney disease (DKD) is the primary cause of chronic kidney disease around the
globe and is one of the main complications in patients with type 1 and 2 diabetes. The …

Therapeutic potential of curcumin in diabetic complications

N Parsamanesh, M Moossavi, A Bahrami… - Pharmacological …, 2018 - Elsevier
Diabetes mellitus is an extremely prevalent endocrine disease and a major global public
health concern. Diabetic complications, such as retinopathy, nephropathy, neuropathy and …

[HTML][HTML] Inflammatory cytokines in diabetic nephropathy

J Donate-Correa, E Martín-Núñez… - Journal of diabetes …, 2015 - hindawi.com
Probably, the most paradigmatic example of diabetic complication is diabetic nephropathy,
which is the largest single cause of end-stage renal disease and a medical catastrophe of …

糖尿病肾病发病机制研究进展

李敏州, 高彦彬, 马鸣飞, 朱智耀, 邹大威, 李勤 - 中国实验方剂学杂志, 2012 - cqvip.com
对糖尿病肾病发病机制的研究进展进行文献整理和分析. 通过检索PubMed
数据库查阅有关糖尿病肾病作用机制的文献, 对近年来国外有关糖尿病肾病发病机制的研究进行 …

The role of inflammatory cytokines in diabetic nephropathy

JF Navarro-Gonzalez… - Journal of the American …, 2008 - journals.lww.com
Cytokines act as pleiotropic polypeptides regulating inflammatory and immune responses
through actions on cells. They provide important signals in the pathophysiology of a range of …

[HTML][HTML] Properties of the glomerular barrier and mechanisms of proteinuria

B Haraldsson, J Nyström, WM Deen - Physiological reviews, 2008 - journals.physiology.org
This review focuses on the intricate properties of the glomerular barrier. Other reviews have
focused on podocyte biology, mesangial cells, and the glomerular basement membrane …